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Protein Overview: avr-15

General Information:
Name(s) found: avr-15 / CE25076 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00000233 locus:avr-15 status:Confirmed UniProt:G5ECH3 protein_id:CAB61021.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 657 amino acids

    Gene Ontology:
    Cellular Component: postsynaptic membrane [IEALink to PubMed article]
    membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: regulation of pharyngeal pumping [IGILink to PubMed article][IMPLink to PubMed articleLink to PubMed article]
    locomotion involved in locomotory behavior [IGILink to PubMed article][IMPLink to PubMed article]
    ion transport [IEALink to PubMed article]
    regulation of action potential [IMPLink to PubMed article]
    transport [IEALink to PubMed article]
    Molecular Function: neurotransmitter receptor activity [IEALink to PubMed article]
    extracellular ligand-gated ion channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIGRLRRGFI LFPQLFLLFV SISSIFLFVL VECKPPKSLN RMRSKGTYNA AAFNSPSMIN  60
   61 NGLLLAGFEN NDTSRETRES YEEYKDDIDH LLEGDLTFYD EGADTAAGDV VITSETPVEK 120
  121 HKEVHFKNEP EEEEIGKEDD GGGEAEEGEY EEENGSDAEE EEESPEKVEP ATSTITTEAQ 180
  181 TTTTPEEVTQ DVSDNIEDDE DARPKSEEHS PKHAASSSDL FEDDDQSTTL ESIARLSAPA 240
  241 HVPIEQPQTS DTEILEHLLT RGYDHRVRPP GEDGTIHGGP VVVSVNMLLR SISKIDNVNM 300
  301 EYSVQLTFRE SWVDKRLSFG VKGDAQPDFL ILTAGQEIWM PDSFFQNEKQ AYKHMIDKPN 360
  361 VLIRVHKDGT ILYSVRISLV LSCPMHLQYY PMDVQQCFID LASYAYTTKD IEYVWKEETP 420
  421 VQLKAGLSSS LPSFQLTNTS TTYCTSKTNT GSYSCLRTII QLRRQFSYYL LQLYIPSCML 480
  481 VIVSWVSFWI DRTAVPARVT LGVTTLLTMT TQSSGINAKL PPVAYIKAID VWIGACMTFI 540
  541 FCALLEFAWV TYIANKQDAN KRARTEREKA ELPFLQNSHN DVWVPREVAE QEREVMTVRM 600
  601 NRRQTNSVWK WIKTKTEWND KSKRADLISR VMFPVLFLTF NISYWTHYGQ YGVAIST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..170] MSA 4.151996 View MSA. No confident structure predictions are available.
    2 View Details [171..226] deduced N/A No confident structure predictions are available.
    3 View Details [227..569] PSI-BLAST 82.09691 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
    4 View Details [570..657] PSI-BLAST 32.69897 Acetylcholine receptor protein, alpha chain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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