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Protein Overview: unc-129

General Information:
Name(s) found: unc-129 / CE24863 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00006852 locus:unc-129 status:Confirmed UniProt:G5EBY8 protein_id:CAB61007.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 407 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [ISSLink to PubMed article]
    Biological Process: axon guidance [IMPLink to PubMed article]
    Molecular Function: growth factor activity [IEALink to PubMed article]
    transforming growth factor beta receptor binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRLPIVLLL SVFSIANCAK VDVDLINETI RDLLHFKSSD PNVTSFHRSS HTLTEHMKNL  60
   61 YENFIDEDSN EDGNLVRAIE PAVGKFEGQE VLVFDVEGFD SHESIMRAEL HFYLRRRDSF 120
  121 ARRRSRQIRA KSVCVNEYCR QQTLKKIRVG GDENLEEYKV IWDATKSVFD SYHLDAKQAV 180
  181 FRITREHSKM RPYAEMIRKS TPFLVIYSKV NHTLDTVSVM KQTEQTKRKR RDLGNEELRE 240
  241 YYNYNSIPLD NDDREPIKRK NGKKNSLSEE ISSEDVWQGF GEETSREERE RIANEELAND 300
  301 VRVVLLQNKN RCHKEGVLVS LKHFGWDRYV IEPKTIETSF CKGKCAKPML TSGKASNHAM 360
  361 LQSLFAAEPV CCAPTNLKSL NFWYRDEKGR TVIRNYSKML IGSCSCL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..67] MSA 1.243996 View MSA. No confident structure predictions are available.
    2 View Details [68..198] MSA 9.371994 View MSA. No confident structure predictions are available.
    3 View Details [199..268] deduced N/A No confident structure predictions are available.
    4 View Details [269..407] PSI-BLAST 37.69897 BONE MORPHOGENETIC PROTEIN-7

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • protein binding
    		•  2.69992067408072 bayes_pls_golite062009
  • receptor binding
    		•  2.08021343073973 bayes_pls_golite062009
  • binding
    		•  1.94128368349087 bayes_pls_golite062009
  • receptor serine/threonine kinase binding
    		•  1.36183834539535 bayes_pls_golite062009
  • transforming growth factor beta receptor binding
    		•  1.15487182590328 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase binding
    		•  1.15487182590328 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.803483953206309 bayes_pls_golite062009
  • growth factor activity
    		•  0.61315906855544 bayes_pls_golite062009
  • protein homodimerization activity
    		•  0.50995657444857 bayes_pls_golite062009
  • vascular endothelial growth factor receptor binding
    		•  0.495685919978181 bayes_pls_golite062009
  • identical protein binding
    		•  0.46701037831689 bayes_pls_golite062009
  • growth factor binding
    		•  0.115424337995679 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle