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Protein Overview: cye-1

General Information:
Name(s) found: cye-1 / CE24832 [WormBase]
Description(s) found:
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  • WBGene00000871 locus:cye-1 G1\/S-specific cyclin-E status:Confirmed UniProt:O01501 protein_id:CCD66921.1 [WormBase]
  • gi|71981552|ref|NP_001021027.1| CYclin E family member (cye-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|3722221|gb|AAC63505.1| cyclin E [Caenorhabditis elegans] [NCBI NR]
  • gi|33112229|sp|O01501.2|CCNE_CAEEL RecName: Full=G1/S-specific cyclin-E [NCBI NR]
  • gi|21902497|gb|AAM78547.1|AF520616_1 cyclin E [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_491941.1| cyclin E, abnormal Eversion of VuLva EVL-10 (60.6 kD) (cye-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|14573916|gb|AAK68235.1|U97194_4 Cyclin e protein 1, isoform a [Caenorhabditis elegans] [NCBI NR]
  • pir||T43050 cyclin E - Caenorhabditis elegans [NCBI NR]
  • (O01501) G1/S-specific cyclin E [Swiss-Prot]
  • G1/S-specific cyclin-E OS=Caenorhabditis elegans GN=cye-1 PE=2 SV=2 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE24832 WBGene00000871 locus:cye-1 cyclin status:Confirmed SW:O01501 protein_id:AAK68235.1 [wormpep150.fasta]
  • 24832 WBGene00000871 locus:cye-1 cyclin status:Confirmed SW:O01501 protein_id:AAK68235.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • cyclin E, abnormal Eversion of VuLva EVL-10 (60.6 kD) (cye-1) [Caenorhabditis elegans]gi|14573916|gb|AAK68235.1| Cyclin e protein 1, isoform a [Caenorhabditis elegans]gi|21902497|gb|AAM78547.1| cyclin E [Caenorhabditis elegans]gi|3722221|gb|AAC63505.1| [nrdb_11152004_Chlamydomonas]
  • locus:cye-1 cyclin status:Confirmed SW:O01501 protein_id:AAK68235.1 [wormpep115.fasta.reversed]
  • CE24832 locus:cye-1 cyclin status:Confirmed [wormpep80.hongbin]
  • CE24832 WBGene00000871 locus:cye-1 cyclin status:Confirmed UniProt:O01501 protein_id:AAK68235.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE24832 WBGene00000871 locus:cye-1 cyclin status:Confirmed UniProt:O01501 protein_id:AAK68235.1| [wormORF-contam.fasta]
  • cyclin E [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • G1/S-specific cyclin-E [nr-271106-contam.fasta]
  • C37A2.4a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Cyclin e protein 1, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE24832 WBGene00000871 locus:cye-1 cyclin status:Confirmed UniProt:O01501 protein_id:CCD66921.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE24832 WBGene00000871 locus:cye-1 status:Confirmed UniProt:O01501 protein_id:CCD66921.1 G1\/S-specific cyclin-E [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 524 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cyclin-dependent protein kinase holoenzyme complex [ISSLink to PubMed article]
    Biological Process: germ cell development [IMPLink to PubMed article]
    embryonic cleavage [IMPLink to PubMed article]
    positive regulation of vulval development [IMPLink to PubMed article]
    positive regulation of cyclin-dependent protein kinase activity [ISSLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    post-embryonic development [IMPLink to PubMed article]
    positive regulation of cell proliferation [IMPLink to PubMed article]
    DNA endoreduplication [IMPLink to PubMed article]
    cytokinesis [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    G1/S transition of mitotic cell cycle [IMPLink to PubMed article]
    Molecular Function: cyclin-dependent protein kinase regulator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGRKSSRTA ERVPTTQKPE RKSAILSPHD ELRERLLETA IDMKENIPQR NTRNSSVGSQ  60
   61 KSDCSETRKR RSTKEGPAAK RHSGEKHRNG SREDSLEYIS EYSDDREVGS SSSQSSRTRG 120
  121 QPLPAMPEEE EVFDKSSSSD NLAESEESHE MVRLEERQDI EEEIEDDFDD EEEDVVNDKE 180
  181 EYEEIESEDE DDYPVQNEGF AVTKRLMNDE HMVTAPTFLS TAKCDGIGSP TKVWSLMVKR 240
  241 DEIPRATRFL LGNHPDMDDE KRRILIDWMM EVCESEKLHR ETFHLAVDYV DRYLESSNVE 300
  301 CSTDNFQLVG TAALFIAAKY EEIYPPKCID FAHLTDSAFT CDNIRTMEVL IVKYIGWSLG 360
  361 PITSIQWLST YLQLLGTGKK NKSDHYEEQN MYVPELLRSE YLEMCKILDF LLFEIDSFTF 420
  421 SYRTIAAAVL FVNYEPTCAV EKATGFMQAQ LEKVIEYVEP VCRAFAKQRQ LLDDVIPKHE 480
  481 SIKSDDSHNI QVYVKRSSME PIVKSERERI QHLKARRLHP QRLF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..220] MSA 3.371996 View MSA. No confident structure predictions are available.
    2 View Details [221..524] PSI-BLAST 49.39794 The structural basis of CDK2 activation by cyclin E


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle