Protein Overview: nhr-23

General Information:
Name(s) found:	nhr-23 / CE24775 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00003622 locus:nhr-23 Nuclear hormone receptor family member nhr-23 status:Confirmed UniProt:P41828 protein_id:CAA95782.2 [WormBase] gi\|71980506\|ref\|NP_001020975.1\| Nuclear Hormone Receptor family member (nhr-23) [Caenorhabditis elegans] [NCBI NR] gi\|6434252\|emb\|CAA95782.2\| C. elegans protein C01H6.5a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] ref\|NP_740887.1\| nuclear Hormone Receptor, regulates molt and epidermal development; related to Drosophila early ecdysone response gene DHR3 (65.3 kD) (nhr-23) [Caenorhabditis elegans] [NCBI NR] gi\|24418858\|sp\|P41828.2\|NHR23_CAEEL RecName: Full=Nuclear hormone receptor family member nhr-23; AltName: Full=Steroid hormone receptor family member chr-3 [NCBI NR] gi\|13274550\|gb\|AAK17974.1\|AF332203_1 nuclear receptor NHR-23 [Caenorhabditis elegans] [NCBI NR] Nuclear hormone receptor family member nhr-23 OS=Caenorhabditis elegans GN=nhr-23 PE=2 SV=2 [Swiss-Prot] (P41828) Nuclear hormone receptor family member nhr-23 (Steroid hormone receptor family member chr-3) [Swiss-Prot] [wormpep67.fasta] CE24775 WBGene00003622 locus:nhr-23 nuclear hormone receptor status:Confirmed SW:P41828 protein_id:CAA95782.2 [wormpep150.fasta] 24775 WBGene00003622 locus:nhr-23 nuclear hormone receptor status:Confirmed SW:P41828 protein_id:CAA95782.2 [wormpep130-phg-ecoli-orf-rand.fasta] nuclear Hormone Receptor, regulates molt and epidermal development; related to Drosophila early ecdysone response gene DHR3 (65.3 kD) (nhr-23) [Caenorhabditis elegans]gi\|6434252\|emb\|CAA95782.2\| Hypothetical protein C01H6.5a [Caenorhabditis elegans]gi\|13 [nrdb_11152004_Chlamydomonas] locus:nhr-23 nuclear hormone receptor status:Confirmed SW:P41828 protein_id:CAA95782.2 [wormpep115.fasta.reversed] CE24775 locus:nhr-23 nuclear hormone receptor status:Confirmed SW:Q17584 protein_id:CAA95782.2 [wormpep80.hongbin] CE24775 WBGene00003622 locus:nhr-23 nuclear hormone receptor status:Confirmed UniProt:P41828 protein_id:CAA95782.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE24775 WBGene00003622 locus:nhr-23 nuclear hormone receptor status:Confirmed UniProt:P41828 protein_id:CAA95782.2\| [wormORF-contam.fasta] nuclear receptor NHR-23 [Caenorhabditis elegans] [nr-271106-contam.fasta] Hypothetical protein C01H6.5a [Caenorhabditis elegans] [nr-271106-contam.fasta] Nuclear hormone receptor family member nhr-23 (Steroid hormone receptor family member chr-3) [nr-271106-contam.fasta] Nuclear Hormone Receptor family member (nhr-23) [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE24775 WBGene00003622 locus:nhr-23 status:Confirmed UniProt:P41828 protein_id:CAA95782.2 Nuclear hormone receptor family member nhr-23 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	588 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA]
Biological Process:	molting cycle, protein-based cuticle [IMP] locomotory behavior [IMP ] nematode larval development [IMP ] post-embryonic body morphogenesis [IMP] regulation of transcription, DNA-dependent [IEA] oviposition [IMP] positive regulation of multicellular organism growth [IMP ] growth [IMP ] reproduction [IMP]
Molecular Function:	DNA binding [IEA] transcription factor activity [IEA] zinc ion binding [IEA] steroid hormone receptor activity [IEA] sequence-specific DNA binding [IEA] steroid binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MACKVTGPNR HLTSVLEMSS FVYWPRSRQQ AHNFPMQAVE QKLADATRTL HAKSSLQPSL  60
   61 SIETPKSKEN DESGCESSNC MFHPHTIKSE PNFCFAREFK SVPDDFRIGG GDLQMGNNSK 120
  121 RLTCVIDTNR VDMAGILPDN MSFRGLPENK SLLVSAQIEV IPCKVCGDKS SGVHYGVITC 180
  181 EGCKGFFRRS QSSIVNYQCP RQKNCVVDRV NRNRCQYCRL KKCIELGMSR DAVKFGRMSK 240
  241 KQREKVEDEV RMHKELAANG LGYQAIYGDY SPPPSHPSYC FDQSMYGHYP SGTSTPVNGY 300
  301 SIAVAATPTT PMPQNMYGAT PSSTNGTQYV AHQATGGSFP SPQVPEEDVA TRVIRAFNQQ 360
  361 HSSYTTQHGV CNVDPDCIPH LSRAGGWELF ARELNPLIQA IIEFAKSIDG FMNLPQETQI 420
  421 QLLKGSVFEL SLVFAAMYYN VDAQAVCGER YSVPFACLIA EDDAEMQLIV EVNNTLQEIV 480
  481 HLQPHQSELA LLAAGLILEQ VSSSHGIGIL DTATIATAET LKNALYQSVM PRIGCMEDTI 540
  541 HRIQDVETRI RQTARLHQEA LQNFRMSDPT SSEKLPALYK ELFTADRP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..156]	MSA	21.430997	View MSA. No confident structure predictions are available.
2	View Details	[157..258]	PSI-BLAST	23.69897	Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
3	View Details	[259..588]	PSI-BLAST	39.221849	hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: nhr-23

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: