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Protein Overview: nhr-23

General Information:
Name(s) found: nhr-23 / CE24775 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00003622 locus:nhr-23 Nuclear hormone receptor family member nhr-23 status:Confirmed UniProt:P41828 protein_id:CAA95782.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 588 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: molting cycle, protein-based cuticle [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    oviposition [IMPLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    steroid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MACKVTGPNR HLTSVLEMSS FVYWPRSRQQ AHNFPMQAVE QKLADATRTL HAKSSLQPSL  60
   61 SIETPKSKEN DESGCESSNC MFHPHTIKSE PNFCFAREFK SVPDDFRIGG GDLQMGNNSK 120
  121 RLTCVIDTNR VDMAGILPDN MSFRGLPENK SLLVSAQIEV IPCKVCGDKS SGVHYGVITC 180
  181 EGCKGFFRRS QSSIVNYQCP RQKNCVVDRV NRNRCQYCRL KKCIELGMSR DAVKFGRMSK 240
  241 KQREKVEDEV RMHKELAANG LGYQAIYGDY SPPPSHPSYC FDQSMYGHYP SGTSTPVNGY 300
  301 SIAVAATPTT PMPQNMYGAT PSSTNGTQYV AHQATGGSFP SPQVPEEDVA TRVIRAFNQQ 360
  361 HSSYTTQHGV CNVDPDCIPH LSRAGGWELF ARELNPLIQA IIEFAKSIDG FMNLPQETQI 420
  421 QLLKGSVFEL SLVFAAMYYN VDAQAVCGER YSVPFACLIA EDDAEMQLIV EVNNTLQEIV 480
  481 HLQPHQSELA LLAAGLILEQ VSSSHGIGIL DTATIATAET LKNALYQSVM PRIGCMEDTI 540
  541 HRIQDVETRI RQTARLHQEA LQNFRMSDPT SSEKLPALYK ELFTADRP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..156] MSA 21.430997 View MSA. No confident structure predictions are available.
    2 View Details [157..258] PSI-BLAST 23.69897 Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
    3 View Details [259..588] PSI-BLAST 39.221849 hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle