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Protein Overview: pen-2

General Information:
Name(s) found: pen-2 / CE24023 [WormBase]
Description(s) found:
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  • WBGene00003975 locus:pen-2 Gamma-secretase subunit pen-2 status:Confirmed UniProt:Q9U357 protein_id:CAB54316.1 [WormBase]
  • pir||T25417 hypothetical protein T28D6.9 - Caenorhabditis elegans [NCBI NR]
  • gi|5824639|emb|CAB54316.1| C. elegans protein T28D6.9, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|37081824|sp|Q9U357.1|PEN2_CAEEL RecName: Full=Gamma-secretase subunit pen-2; AltName: Full=Presenilin enhancer protein 2 [NCBI NR]
  • gi|17555348|ref|NP_499459.1| Presenilin ENhancer (enhancer of sel-12(null)) family member (pen-2) [Caenorhabditis elegans] [NCBI NR]
  • Gamma-secretase subunit pen-2 OS=Caenorhabditis elegans GN=pen-2 PE=2 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE24023 WBGene00003975 locus:pen-2 status:Partially_confirmed SW:Q9U357 protein_id:CAB54316.1 [wormpep150.fasta]
  • 24023 WBGene00003975 locus:pen-2 status:Partially_confirmed SW:Q9U357 protein_id:CAB54316.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • presenilin ENhancer (enhancer of sel-12 null) PEN-2, presenilin enhancer (pen-2) [Caenorhabditis elegans]gi|5824639|emb|CAB54316.1| Hypothetical protein T28D6.9 [Caenorhabditis elegans]gi|7508670|pir||T25417 hypothetical protein T28D6.9 - Caenorhabditis [nrdb_11152004_Chlamydomonas]
  • locus:pen-2 status:Partially_confirmed SW:Q9U357 protein_id:CAB54316.1 [wormpep115.fasta.reversed]
  • CE24023 status:Partially_confirmed TR:Q9U357 protein_id:CAB54316.1 [wormpep80.hongbin]
  • CE24023 WBGene00003975 locus:pen-2 status:Confirmed UniProt:Q9U357 protein_id:CAB54316.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE24023 WBGene00003975 locus:pen-2 status:Confirmed UniProt:Q9U357 protein_id:CAB54316.1| [wormORF-contam.fasta]
  • Gamma-secretase subunit pen-2 (Presenilin enhancer protein 2) [nr-271106-contam.fasta]
  • Presenilin ENhancer (enhancer of sel-12(null)) family member (pen-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein T28D6.9 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE24023 WBGene00003975 locus:pen-2 status:Confirmed SW:Q9U357 protein_id:CAB54316.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE24023 WBGene00003975 locus:pen-2 status:Confirmed UniProt:Q9U357 protein_id:CAB54316.1 Gamma-secretase subunit pen-2 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 101 amino acids

    Gene Ontology:
    Cellular Component: membrane [IDA]
    integral to membrane [IEALink to PubMed article]
    Biological Process: germ cell development [IGI]
    hermaphrodite genitalia development [IMP]
    pharynx development [IMP]
    Notch signaling pathway [IMP]
    nematode larval development [IMP]
    embryonic morphogenesis [IMP]
    embryonic development ending in birth or egg hatching [IMP]
    cell fate commitment [IGI]
    growth [IMP]
    reproduction [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDISKLTDVK KVDLCKKYFL IGACFLPLVW IVNTFWFFSD AFCKPINAHR RQIRKYVIAS  60
   61 IVGSIFWIIV LSAWEIFFQH YRAQGLVWTD FLTFVFPTGR V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] deduced N/A Confident ab initio structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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