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Protein Overview: mab-20

General Information:
Name(s) found: mab-20 / CE22926 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00003111 locus:mab-20 Semaphorin-2A status:Confirmed UniProt:Q95XP4 protein_id:CCD67974.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 658 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: multicellular organismal development [IEALink to PubMed article]
    tail tip morphogenesis [IGILink to PubMed article][IMPLink to PubMed article]
    regulation of cell adhesion [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: receptor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRNFLVFSVI FIAYNSCEAA NIQADNTFAD PNIGEFRELL IDPKAGALFV GSEGAIFRLW  60
   61 AYNINDTGEN VFAKKQLVLS ESEESECRST ASDERLCRPS TRFLAFTNNL DSIYVCSSVG 120
  121 MRPEIRVLDS LSLRDQQEPR TEIGICVVDP TFNFTAVVVD SGNPEDATSV YSGIRTGMGG 180
  181 ENHLIYRPPL TKNGKQLHAS IRTIYSDNKW LNEPQFVGSF DVGQHVFFFF REIAHDNSFG 240
  241 ERIVHSRVAR VCKKDIGGRN VLRQVWTSFV KARLNCSVSA NFPFYFDHIQ SVKRVDKHGE 300
  301 TYFYATFSTS ETAFTSSAIC MFQLSSINHL LDTGLLMEET ANGQFSVTAD EIPAHRPGTC 360
  361 SQNSHSISDT DLHFAKTHLL VSDSISGGTP ILPLRDHVFT HIVVDQLPNQ NVIFAFDSAN 420
  421 RRVWKISHWK EGNEWKSNLI EEKSLKIAAS RINDVALLPA EFFFVTSGAG VSQFSVARCS 480
  481 EQPSCALCSL DPYCSWNAVN SKCSLKTKTN EKSVGWISSS WAGRISPECS AVEKLTVKDV 540
  541 YLGDGLRLVG AKNGVWQKDG RSVESGQRHV VTRNGELVVL DAQLEDAGTY ECLRDNIILV 600
  601 RARIVVHENC ARPTSVAEYR SCQREWCKKA DAYKAALNIW SDSNKKNVQC KANTSSAH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..658] PSI-BLAST 107.0 The ligand-binding face of the semaphorins revealed by the high resolution crystal structure of SEMA4D

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • antigen binding
    		•  4.06466268219034 bayes_pls_golite062009
  • receptor binding
    		•  1.69538764684177 bayes_pls_golite062009
  • binding
    		•  1.30764958471421 bayes_pls_golite062009
  • chemorepellent activity
    		•  1.00465333987168 bayes_pls_golite062009
  • protein binding
    		•  0.874236375624771 bayes_pls_golite062009
  • platelet-derived growth factor receptor binding
    		•  0.68620352874827 bayes_pls_golite062009
  • integrin binding
    		•  0.47704880649188 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  0.237137098219707 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
    		•  0.0579877383828277 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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