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View Structure Prediction Details

Protein: mab-20
Organism: Caenorhabditis elegans
Length: 658 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mab-20.

Description E-value Query
Range
Subject
Range
gi|114614264 - gi|114614264|ref|XP_001160811.1| PREDICTED: semaphorin 3A isoform 2 [Pan troglodytes]
454.0 [0..8] [658..30]

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Predicted Domain #1
Region A:
Residues: [1-658]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRNFLVFSVI FIAYNSCEAA NIQADNTFAD PNIGEFRELL IDPKAGALFV GSEGAIFRLW  60
   61 AYNINDTGEN VFAKKQLVLS ESEESECRST ASDERLCRPS TRFLAFTNNL DSIYVCSSVG 120
  121 MRPEIRVLDS LSLRDQQEPR TEIGICVVDP TFNFTAVVVD SGNPEDATSV YSGIRTGMGG 180
  181 ENHLIYRPPL TKNGKQLHAS IRTIYSDNKW LNEPQFVGSF DVGQHVFFFF REIAHDNSFG 240
  241 ERIVHSRVAR VCKKDIGGRN VLRQVWTSFV KARLNCSVSA NFPFYFDHIQ SVKRVDKHGE 300
  301 TYFYATFSTS ETAFTSSAIC MFQLSSINHL LDTGLLMEET ANGQFSVTAD EIPAHRPGTC 360
  361 SQNSHSISDT DLHFAKTHLL VSDSISGGTP ILPLRDHVFT HIVVDQLPNQ NVIFAFDSAN 420
  421 RRVWKISHWK EGNEWKSNLI EEKSLKIAAS RINDVALLPA EFFFVTSGAG VSQFSVARCS 480
  481 EQPSCALCSL DPYCSWNAVN SKCSLKTKTN EKSVGWISSS WAGRISPECS AVEKLTVKDV 540
  541 YLGDGLRLVG AKNGVWQKDG RSVESGQRHV VTRNGELVVL DAQLEDAGTY ECLRDNIILV 600
  601 RARIVVHENC ARPTSVAEYR SCQREWCKKA DAYKAALNIW SDSNKKNVQC KANTSSAH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 107.0
Match: 1olzA
Description: The ligand-binding face of the semaphorins revealed by the high resolution crystal structure of SEMA4D
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
antigen binding 4.06466268219034 bayes_pls_golite062009
receptor binding 1.69538764684177 bayes_pls_golite062009
binding 1.30764958471421 bayes_pls_golite062009
chemorepellent activity 1.00465333987168 bayes_pls_golite062009
protein binding 0.874236375624771 bayes_pls_golite062009
platelet-derived growth factor receptor binding 0.68620352874827 bayes_pls_golite062009
integrin binding 0.47704880649188 bayes_pls_golite062009
fibroblast growth factor 1 binding 0.237137098219707 bayes_pls_golite062009
fibroblast growth factor receptor activity 0.0579877383828277 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle