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Protein Overview: CE20851

General Information:
Name(s) found: CE20851 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00018783 locus:cbs-2 status:Partially_confirmed UniProt:Q9N4K2 protein_id:CCD71742.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 755 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: tryptophan biosynthetic process [IEALink to PubMed article]
    threonine biosynthetic process [IEALink to PubMed article]
    metabolic process [IEALink to PubMed article]
    cysteine biosynthetic process via cystathionine [IEALink to PubMed article]
    cysteine biosynthetic process from serine [IEALink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IEALink to PubMed article]
    tryptophan synthase activity [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    cystathionine beta-synthase activity [IEALink to PubMed article]
    threonine synthase activity [IEALink to PubMed article]
    cysteine synthase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCLPTIKAFK TILDAGSHRA TQLVPLKKLK AEFQLKSDIY VKLEYLNISG SLEDRAAHRA  60
   61 FEMSNGIQRG DEVYVTAGGS SAVSYATVAA VKGVRLTAHA PPGAFDQVRT ILSTLGTKIV 120
  121 ELPVSNFREA RLQADLLAKR RGVYNLDGIC EKAAFLANLE GTAPEIEKAG KTSAVVVPLD 180
  181 AGGASAAAGI AAYFLKDQKT TVVGVRSSAS ASASAPAPET EVLLQKYKVE IRDAPESYTF 240
  241 TRHLIETEGI MAGPSSGAAV LEAIKLAKDL PAGSVVVVVL MDGIRDYLDA DWMKVNGKKP 300
  301 IKPREIFDPK VLDYDPTKMV GEWKSSSKFR PERPLVLDSV LDAIGKTPLV KLQHVPKAHG 360
  361 VRCNVYVKCE FLNAGGSTKD RIAKKMVEIA EKTGKPGALT PGATTLIEPT SGNTGIGLSL 420
  421 VAAVRGYKCL ITMPEKMSKE KSTTLSVLGS TIVRTPNEAA FNSPSSHIGV ALRLKHEIPG 480
  481 AVILDQYCNP GNPLAHYEET AEEILWDMGD RKIDLVVLGA GTGGTITGIS RKIHERRPNA 540
  541 IVVGVDPNGS ILTGPTTGPA PDFYEVEGIG YDFIPGTLDE KSVDSWLKSD DKESFLMARE 600
  601 IIRTEGILCG GSSGCAVHYA LEQCRKLDLP EDANVVVLLP DGIRNYLTKF LDDDWMKARG 660
  661 FFGFCIKNDR KCIFPAIRPV KLVKIWIFRH IPCKIDNRSH NSNNRSHIRR PAQSRSTAPH 720
  721 SNPPATPARE GGPDNETPCT LTLAASRSLR SRIFY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..287] PSI-BLAST 41.221849 Crystal Structure of S.pombe Serine Racemase
    2 View Details [288..755] PSI-BLAST 104.0 Cystathionine beta-synthase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cysteine synthase activity
    		•  5.18562032111987 bayes_pls_golite062009
  • catalytic activity
    		•  2.38994231321972 bayes_pls_golite062009
  • lyase activity
    		•  1.87743897464083 bayes_pls_golite062009
  • cystathionine beta-synthase activity
    		•  1.4517088142802 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  1.04832999357666 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.923824749425553 bayes_pls_golite062009
  • threonine synthase activity
    		•  0.727838845253199 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.476674617721478 bayes_pls_golite062009
  • L-threonine ammonia-lyase activity
    		•  0.37325071016009 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  0.249761226675912 bayes_pls_golite062009
    2
    Term Confidence Notes
  • cysteine synthase activity
    		•  5.18562032111987 bayes_pls_golite062009
  • catalytic activity
    		•  2.38994231321972 bayes_pls_golite062009
  • lyase activity
    		•  1.87743897464083 bayes_pls_golite062009
  • cystathionine beta-synthase activity
    		•  1.4517088142802 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  1.04832999357666 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.923824749425553 bayes_pls_golite062009
  • threonine synthase activity
    		•  0.727838845253199 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.476674617721478 bayes_pls_golite062009
  • L-threonine ammonia-lyase activity
    		•  0.37325071016009 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  0.249761226675912 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle