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Protein Overview: unc-25

General Information:
Name(s) found: unc-25 / CE20226 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00006762 locus:unc-25 status:Confirmed UniProt:G5EDB7 protein_id:CAA21537.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 508 amino acids

    Gene Ontology:
    Cellular Component: inhibitory synapse [IDALink to PubMed article]
    synaptic vesicle [IDALink to PubMed article]
    neuronal cell body [IDALink to PubMed article]
    axon [IDALink to PubMed article]
    Biological Process: carboxylic acid metabolic process [IEALink to PubMed article]
    synaptic transmission, GABAergic [IGILink to PubMed article]
    gamma-aminobutyric acid biosynthetic process [ISSLink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IEALink to PubMed article][ISSLink to PubMed article]
    glutamate decarboxylase activity [ISSLink to PubMed article]
    carboxy-lyase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSAAADESD AVLENLIAKE ILPQTGNWEG TEEFLNRIVQ VLLKYIKDQN DRDQKILEFH  60
   61 HPDKMQMLMD LSIPEKPESL LKLVKSCEDV LRLGVRTGHP RFFNQISCGL DLVSMAGEWL 120
  121 TATANTNMFT YEIAPVFILM EKSVMARMWE AVGWDPEKAD GIFAPGGAIA NLYAMNAARH 180
  181 QLWPRSKHLG MKDIPTLCCF TSEDSHYSIK SASAVLGIGA DYCFNIPTDK NGKMIPEALE 240
  241 AKIIECKKEG LTPFFACCTA GSTVYGAFDP LERVANICER HKLWFHVDAA WGGGMLLSPE 300
  301 HRYKLAGIER ANSVTWNPHK LMGALLQCSA CLFRQDGLLF QCNQMSADYL FQQDKPYDVS 360
  361 FDTGDKAIQC GRHNDVFKLW LMWKSKGMEG YRQQINKLMD LANYFTRRIK ETEGFELIIE 420
  421 NPEFLNICFW YVPSKIRNLE PAEMRARLEK IAPKIKAGMM QRGTTMVGYQ PDKQRPNFFR 480
  481 MIISNQAITR EDLDFLIKEI VDIGESLE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..508] PSI-BLAST 109.0 No description for 2okjA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle