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Protein Overview: pap-1

General Information:
Name(s) found: pap-1 / CE20204 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00012528 locus:pap-1 status:Confirmed UniProt:Q9U2P3 protein_id:CAA16309.3 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 655 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    transcription [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed articleLink to PubMed article]
    RNA polyadenylation [IEALink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: nucleotidyltransferase activity [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]
    polynucleotide adenylyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATEKDKTP LLGVSQPISL AHPDSKDIAQ TTLLIETLKK FGSYEPKEET EQRMEVLRNL  60
   61 NRLVKEWVKN VTAMKIPNGE GVNAGGKLFT FGSYRLGVHS SGADIDTLAV VPRHIDRSDF 120
  121 FTSFKEMLNN DPNVTELHGV EEAFVPVMKL KYSGVELDIL FARLALKEVP DTQELSDDNL 180
  181 LRNLDQESVR SLNGCRVAEQ LLKLVPRQKE FCVTLRAIKL WAKNHGIYSN SMGFFGGITW 240
  241 AILVARACQL YPNASPSRLV HRMFFIFSTW TWPHPVVLNE MNNDRNDIPT LCELVWDPRR 300
  301 KNTDRFHVMP IITPAFPEQN STHNVTRSTA TVIKNEICEA LEICRDISEG KSKWTALFEE 360
  361 VNFFSRYKHF IALIMAAPNE EEELNYGGFL ESRIRLLVQS LERNQDIIIA HNDPNKHKPS 420
  421 PNAKFDVNPE NKRVTVWFIG LEFAEHAKTL DLTNEIQRFK TNVELQASNV KGIGPNCQVQ 480
  481 IDMFYVKRNS LIQVISAADL RRGRRWKKVV PIATNTSVSS STPRSVVRTT STSSVPTTPT 540
  541 GLAAPKTPLS ASVSATNEPD STTNGTPLSR KRSMDEESST TVTSQISDES VPKKKTRDDT 600
  601 LEENRVSMVV EVSNVVVEQR TKVVQEIVDL QADNGLNTSN GLEASEQKME VPQSV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..513] PSI-BLAST 166.0 Poly(A) polymerase, middle domain; Poly(A) polymerase N-terminal, catalytic domain; Poly(A) polymerase, C-terminal domain
    2 View Details [514..655] FFAS03 1.51 No description for 2j63A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.122769147009 bayes_pls_golite062009
  • RNA binding
    		•  1.07207584601969 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.92178707322923 bayes_pls_golite062009
  • polynucleotide adenylyltransferase activity
    		•  0.911825870004661 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.667889614569279 bayes_pls_golite062009
  • transferase activity
    		•  0.63270331673446 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.48

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle