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View Structure Prediction Details

Protein: pap-1
Organism: Caenorhabditis elegans
Length: 655 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pap-1.

Description E-value Query
Range
Subject
Range
gi|73964450 - gi|73964450|ref|XP_537551.2| PREDICTED: similar to poly(A) polymerase alpha [Canis familiaris]
619.0 [0..2] [654..83]

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Predicted Domain #1
Region A:
Residues: [1-513]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATEKDKTP LLGVSQPISL AHPDSKDIAQ TTLLIETLKK FGSYEPKEET EQRMEVLRNL  60
   61 NRLVKEWVKN VTAMKIPNGE GVNAGGKLFT FGSYRLGVHS SGADIDTLAV VPRHIDRSDF 120
  121 FTSFKEMLNN DPNVTELHGV EEAFVPVMKL KYSGVELDIL FARLALKEVP DTQELSDDNL 180
  181 LRNLDQESVR SLNGCRVAEQ LLKLVPRQKE FCVTLRAIKL WAKNHGIYSN SMGFFGGITW 240
  241 AILVARACQL YPNASPSRLV HRMFFIFSTW TWPHPVVLNE MNNDRNDIPT LCELVWDPRR 300
  301 KNTDRFHVMP IITPAFPEQN STHNVTRSTA TVIKNEICEA LEICRDISEG KSKWTALFEE 360
  361 VNFFSRYKHF IALIMAAPNE EEELNYGGFL ESRIRLLVQS LERNQDIIIA HNDPNKHKPS 420
  421 PNAKFDVNPE NKRVTVWFIG LEFAEHAKTL DLTNEIQRFK TNVELQASNV KGIGPNCQVQ 480
  481 IDMFYVKRNS LIQVISAADL RRGRRWKKVV PIA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 166.0
Match: 1f5aA
Description: Poly(A) polymerase, middle domain; Poly(A) polymerase N-terminal, catalytic domain; Poly(A) polymerase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.122769147009 bayes_pls_golite062009
RNA binding 1.07207584601969 bayes_pls_golite062009
nucleotidyltransferase activity 0.92178707322923 bayes_pls_golite062009
polynucleotide adenylyltransferase activity 0.911825870004661 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.667889614569279 bayes_pls_golite062009
transferase activity 0.63270331673446 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [514-655]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNTSVSSSTP RSVVRTTSTS SVPTTPTGLA APKTPLSASV SATNEPDSTT NGTPLSRKRS  60
   61 MDEESSTTVT SQISDESVPK KKTRDDTLEE NRVSMVVEVS NVVVEQRTKV VQEIVDLQAD 120
  121 NGLNTSNGLE ASEQKMEVPQ SV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.51
Match: 2j63A
Description: No description for 2j63A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle