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Protein Overview: ape-1

General Information:
Name(s) found: ape-1 / CE19874 [WormBase]
Description(s) found:
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  • WBGene00000146 locus:ape-1 Apoptotic enhancer 1 protein status:Confirmed UniProt:Q9XVN3 protein_id:CAB03115.1 [WormBase]
  • pir||T22316 hypothetical protein F46F3.4 - Caenorhabditis elegans [NCBI NR]
  • gi|3877221|emb|CAB03115.1| C. elegans protein F46F3.4, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|34098765|sp|Q9XVN3.1|IASPP_CAEEL RecName: Full=Apoptotic enhancer 1 protein; AltName: Full=Inhibitor member of the ASPP family; Short=Protein iASPP; AltName: Full=Ce-iASPP [NCBI NR]
  • gi|17561074|ref|NP_505955.1| APoptosis Enhancer family member (ape-1) [Caenorhabditis elegans] [NCBI NR]
  • (Q9XVN3) Apoptotic enhancer 1 protein (Inhibitor member of the ASPP family) (Protein iASPP) (Ce-iASPP) [Swiss-Prot]
  • Apoptotic enhancer 1 protein OS=Caenorhabditis elegans GN=ape-1 PE=1 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE19874 WBGene00000146 locus:ape-1 P53-binding protein like status:Partially_confirmed SW:Q9XVN3 protein_id:CAB03115.1 [wormpep150.fasta]
  • 19874 WBGene00000146 locus:ape-1 P53-binding protein like status:Partially_confirmed SW:Q9XVN3 protein_id:CAB03115.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • APoptosis Enhancer APE-1, RelA-associated inhibitor (ape-1) [Caenorhabditis elegans]gi|3877221|emb|CAB03115.1| Hypothetical protein F46F3.4 [Caenorhabditis elegans]gi|7503591|pir||T22316 hypothetical protein F46F3.4 - Caenorhabditis elegansgi|34098765| [nrdb_11152004_Chlamydomonas]
  • locus:ape-1 P53-binding protein like status:Partially_confirmed SW:Q9XVN3 protein_id:CAB03115.1 [wormpep115.fasta.reversed]
  • CE19874 P53-binding protein like status:Partially_confirmed TR:Q9XVN3 protein_id:CAB03115.1 [wormpep80.hongbin]
  • CE19874 WBGene00000146 locus:ape-1 P53-binding protein like status:Confirmed UniProt:Q9XVN3 protein_id:CAB03115.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE19874 WBGene00000146 locus:ape-1 P53-binding protein like status:Confirmed UniProt:Q9XVN3 protein_id:CAB03115.1| [wormORF-contam.fasta]
  • Hypothetical protein F46F3.4 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Apoptotic enhancer 1 protein (Inhibitor member of the ASPP family) (Protein iASPP) (Ce-iASPP) [nr-271106-contam.fasta]
  • APoptosis Enhancer family member (ape-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE19874 WBGene00000146 locus:ape-1 P53-binding protein like status:Confirmed SW:Q9XVN3 protein_id:CAB03115.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE19874 WBGene00000146 locus:ape-1 status:Confirmed UniProt:Q9XVN3 protein_id:CAB03115.1 Apoptotic enhancer 1 protein [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 769 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: cell death [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTTSSGGGI GYPANNGVTQ VSLIHSSDSV RTVSTAPIYR PTSSMASTMA HKSSTAPFIS  60
   61 ANQRMSKPPV RVVAQPPPPH PQALSQQYHQ QNPMMMYSAP NTRPHVIPTM QVQPTMAAQI 120
  121 KRNNPVNAQF QNPSEMIADY GVKPQSVEMV QRVRAVRRQV ADEETELRRL RELEHETAQL 180
  181 QNKNYGRERE LNVQGSMLKE AQLELRNASM RAQSLNKHLE EMYRRRQTAA AAALVEQRKM 240
  241 QQHQILLARA ANQVSTQEVI RPRASVEPFQ VNNTQQQQPS PQMMKSEEFS EKRDLNGQTG 300
  301 SYDAIDGSGD HQKIPTEPSY LAPCKENQQK YSELSKMAST DPHSNHSSPS TSSQKAPTLI 360
  361 TFSPPSFEQK INSSTMTRDS PFVERPTSFG DSLDESRLRS GKTDLVSLRS DSLKATKRRS 420
  421 WAASEGTSMS EAEMIHRLLD EQRRGRSHFI PQLPTSQEEP SAITSETYAE EVVNSESKQV 480
  481 ATSSDSTNNL ELPTEQMVLG SDTTTEEDAS SCSTRSDDGQ NLEMEVAIER RTVKGILRRP 540
  541 NEKMNKGRIE FDPLALLLDA ALEGELDLVR SSASKLTDVS QANDEGITAL HNAICAGHYE 600
  601 IVRFLIENDA DVNAQDSDGW TPLHCAASCN NLPMVRQLVE GGGCVLASTL SDMETPVEKC 660
  661 EEDEDGYDGC LKYLSAAHNS TGSINTGKVY AAYGYEAAFE DELSFDAGDE LTVIEKDKVD 720
  721 KNWWTCEKNN GEKGQVPRTY LALYPSLKYR KKLNFVMFDL PLESNNNVE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..166] deduced N/A No confident structure predictions are available.
    2 View Details [167..284] deduced N/A No confident structure predictions are available.
    3 View Details [285..348] deduced N/A No confident structure predictions are available.
    4 View Details [349..643] PSI-BLAST 27.69897 Transcription factor inhibitor I-kappa-B-beta, IKBB
    5 View Details [644..769] PSI-BLAST 32.39794 53BP2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • protein binding
    		•  1.85450951074782 bayes_pls_golite062009
  • binding
    		•  1.67882758018256 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle