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Protein Overview: CE19434

General Information:
Name(s) found: CE19434 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00018678 Probable tyrosyl-DNA phosphodiesterase status:Confirmed UniProt:Q9TXV7 protein_id:CCD71624.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 451 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: DNA repair [IEALink to PubMed article]
    metabolic process [IEALink to PubMed article]
    Molecular Function: catalytic activity [IEALink to PubMed article]
    phosphoric diester hydrolase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRTIQETPG PSSTTVPPPK KLNSQRNGSN LEPGSIYFTP IGGISVPRQE SESSRSLDEI  60
   61 LADIRPINSL HFSFMLDFEF LIGSYPPSLR EYPITLVVGA PDAPDLLKCT KNQKLVTVVG 120
  121 ASLPIPFGTH HTKMSILEDE DGRFHVIVST ANLVPDDWEF KTQQFYYNFG VKIASGTVPR 180
  181 SDFQDDLLEY LSMYRNQLDT WKQLLQKVDF SQISDRLIFS TPGYHTDPPT QRPGHPRLFR 240
  241 ILSEKFPFDA SYEHTERCTF VAQCSSIGSL GSAPINWFRG QFLQSLEGAN PSPKQKPAKM 300
  301 YLVFPSVEDV RTSCQGYAGG CSVPYRNSVH ARQKWLQGNM CKWRSNAKRR TNAVPHCKTY 360
  361 VKYDKKVAIW QLLTSANLSK AAWGEVSFNK SKNVEQLMIR SWEMGVLITD PSRFNIPFDY 420
  421 PLVPYSATDE PFVTDKKHEK PDILGCIWTP P

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..451] PSI-BLAST 155.0 human Tyrosyl DNA phosphodiesterase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3'-tyrosyl-DNA phosphodiesterase activity
    		•  1.46693175347055 bayes_pls_golite062009
  • tyrosyl-DNA phosphodiesterase activity
    		•  1.46693175347055 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.41591686174898 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  1.29668490323599 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  1.29429720882252 bayes_pls_golite062009
  • catalytic activity
    		•  1.29236214516383 bayes_pls_golite062009
  • binding
    		•  1.26667168593698 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.926017334343152 bayes_pls_golite062009
  • DNA binding
    		•  0.840595330626189 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.235198647671849 bayes_pls_golite062009
  • protein binding
    		•  0.162885453822356 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle