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Protein Overview: cki-2

General Information:
Name(s) found: cki-2 / CE18928 [WormBase]
Description(s) found:
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  • WBGene00000517 locus:cki-2 status:Confirmed UniProt:Q22198 protein_id:CAA90670.1 [WormBase]
  • pir||T24499 hypothetical protein T05A6.2 - Caenorhabditis elegans [NCBI NR]
  • gi|71994449|ref|NP_495642.3| CKI family (Cyclin-dependent Kinase Inhibitor) family member (cki-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|3879402|emb|CAA90670.1| C. elegans protein T05A6.2a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • Hypothetical protein T05A6.2a [Caenorhabditis elegans]gi|7507135|pir||T24499 hypothetical protein T05A6.2 - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas]
  • CE18928 WBGene00000517 locus:cki-2 posterior sex combs protein-like domain status:Confirmed TR:Q22198 protein_id:CAA90670.1 [wormpep150.fasta]
  • 18928 WBGene00000517 locus:cki-2 posterior sex combs protein-like domain status:Confirmed TR:Q22198 protein_id:CAA90670.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • locus:cki-2 posterior sex combs protein-like domain status:Partially_confirmed TR:Q22198 protein_id:CAA90670.1 [wormpep115.fasta.reversed]
  • CE18928 locus:cki-2 posterior sex combs protein-like domain status:Partially_confirmed TR:Q22198 protein_id:CAA90670.1 [wormpep80.hongbin]
  • CE18928 WBGene00000517 locus:cki-2 posterior sex combs protein-like domain status:Confirmed UniProt:Q22198_CAEEL protein_id:CAA90670.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE18928 WBGene00000517 locus:cki-2 posterior sex combs protein-like domain status:Confirmed UniProt:Q22198_CAEEL protein_id:CAA90670.1| [wormORF-contam.fasta]
  • Hypothetical protein T05A6.2a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CKI family (Cyclin-dependent Kinase Inhibitor) family member (cki-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE18928 WBGene00000517 locus:cki-2 posterior sex combs protein-like domain status:Confirmed UniProt:Q22198 protein_id:CAA90670.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE18928 WBGene00000517 locus:cki-2 status:Confirmed UniProt:Q22198 protein_id:CAA90670.1 [wormpep246-ecoli-contam.fasta]
  • Isoform of G5EEJ2, CKI family (Cyclin-dependent Kinase Inhibitor) OS=Caenorhabditis elegans GN=cki-2 PE=4 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 258 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article][IEALink to PubMed article]
    Biological Process: cell cycle arrest [IEALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: cyclin-dependent protein kinase inhibitor activity [IEALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAATTAGDGK RKAARCLFGK PDPEEVSRQL NSSLEEMYKK DSRKFNFDFS GGVPIVGSRG  60
   61 DYEFESISAS EVPSFYREKI VRPRKIIARR NSTPVSDTVE MPSESPPVVE SNETPLLIAS 120
  121 TSTEVTVYEK PVTRSSAAKQ SIEQQETYNL KQTKLTNYMP VRKRRSETCL VTAAVSMSRS 180
  181 VSIDSSMESC KEKRGSKIVH NNKGAPKRPL RFVASNVPKS AQSSTSDTVL VSSPRSPPAK 240
  241 KMTTSTRRSR RPIEAGDF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..147] PSI-BLAST 32.30103 P27(KIP1) fragment 22-106
    2 View Details [148..258] MSA 2.021997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle