Protein Overview: apr-1

General Information:
Name(s) found:	apr-1 / CE18016 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00000156 locus:apr-1 Adenomatous polyposis coli protein-related protein 1 status:Confirmed UniProt:Q21227 protein_id:CAB00048.1 [WormBase] pir\|\|T23330 hypothetical protein K04G2.8b - Caenorhabditis elegans [NCBI NR] gi\|71988399\|ref\|NP_001021547.1\| APC Related family member (apr-1) [Caenorhabditis elegans] [NCBI NR] gi\|3878270\|emb\|CAB00048.1\| C. elegans protein K04G2.8b, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|205689019\|sp\|Q21227.2\|APR1_CAEEL RecName: Full=Adenomatous polyposis coli protein-related protein 1; Short=APC-related protein 1 [NCBI NR] Adenomatous polyposis coli protein-related protein 1 OS=Caenorhabditis elegans GN=apr-1 PE=1 SV=2 [Swiss-Prot] [wormpep67.fasta] Hypothetical protein K04G2.8b [Caenorhabditis elegans]gi\|7505296\|pir\|\|T23330 hypothetical protein K04G2.8b - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas] CE18016 WBGene00000156 locus:apr-1 status:Confirmed TR:O62302 protein_id:CAB00048.1 [wormpep150.fasta] 18016 WBGene00000156 locus:apr-1 status:Partially_confirmed TR:O62302 protein_id:CAB00048.1 [wormpep130-phg-ecoli-orf-rand.fasta] CE18016 WBGene00000156 locus:apr-1 status:Partially_confirmed TR:O62302 protein_id:CAB00048.1 [wormpep132.fasta] 18016 WBGene00000156 locus:apr-1 status:Confirmed TR:O62302 protein_id:CAB00048.1 [wormpep150-phg-orf-ecoli-rand.fasta] locus:apr-1 status:Partially_confirmed TR:O62302 protein_id:CAB00048.1 [wormpep115.fasta.reversed] CE18016 locus:apr-1 status:Partially_confirmed TR:O62302 protein_id:CAB00048.1 [wormpep80.hongbin] CE18016 WBGene00000156 locus:apr-1 status:Confirmed UniProt:O62302_CAEEL protein_id:CAB00048.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE18016 WBGene00000156 locus:apr-1 status:Confirmed UniProt:O62302_CAEEL protein_id:CAB00048.1\| [wormORF-contam.fasta] APC Related family member (apr-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] Hypothetical protein K04G2.8b [Caenorhabditis elegans] [nr-271106-contam.fasta] CE18016 WBGene00000156 locus:apr-1 status:Confirmed UniProt:Q21227 protein_id:CAB00048.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE18016 WBGene00000156 locus:apr-1 status:Confirmed UniProt:Q21227 protein_id:CAB00048.1 Adenomatous polyposis coli protein-related protein 1 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	1188 amino acids
Gene Ontology:
Cellular Component:	adherens junction [IDA] cytoplasm [IDA]
Biological Process:	negative regulation of vulval development [IGI][IMP] embryonic cleavage [IMP] spindle organization [IMP] vulval development [IGI][IMP] embryonic development ending in birth or egg hatching [IMP ] post-embryonic body morphogenesis [IMP ] positive regulation of transcription from RNA polymerase II promoter [IMP] reproduction [IMP] growth [IMP ] locomotory behavior [IMP ] nematode larval development [IMP ] embryonic morphogenesis [IMP] endodermal cell fate specification [IGI][IMP] negative regulation of Wnt receptor signaling pathway [IGI] positive regulation of Wnt receptor signaling pathway [IGI] regulation of cell migration [IMP] regulation of embryonic cell shape [IMP] cell fate specification [IGI][IMP]
Molecular Function:	beta-catenin binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSSSDENE TTIHRTGSNT GGSGIYSQPR AGSSKRTSNV RHDVSDVDDE EEHYARFRED  60
   61 TAIEVDDAIT VLLSSLHFEH KRDIVPTDED DNKLRELHEK IFALITSESD VNRKRRLKKA 120
  121 LPASNCVREQ VYYLRRKPST PPASYYHRLN AALHTIVKES FGEEYRKVAT VLGLVEALAE 180
  181 VLILEVHTFG INETNPGEHR NIRKLIANAL TNLTYGQIHS KRRLCSYDGF IRCVVRIVIE 240
  241 SPNITQVYAG LIRNLSWNAD SGMSEALQPT VHALSIAAVH AHTHRFDVTA TLSALWNLAG 300
  301 HSVENKRTIC DTPNCLKVLA SLLSPDARFT SLVDSATGIL KYVSQYLANT STHLELRSLL 360
  361 ITRMLTLLKS ASFTCVTNTL GAIANLIVKD PHMQQMIRQD MAAVQQLNVL RNSNRDDIRT 420
  421 AVKSVLNTLN QPCSHRYGDM SHSVGGGATG MQMLSEPQLQ MQTSHHAYHG TASPRLLSLR 480
  481 ATRASPGKYI QPQAQQQLIQ TPQVDQRSSS LPRHFAVQRN GFVMAQSYNQ QMDQHQQQQM 540
  541 IYQLQQQQQI MFQTEDQAQM EHHQQIMYLQ QQQQQFHQIQ QQQQMQKAQE ADPVPPTDDD 600
  601 LDIPTSTVMG TRSNSERSLG SMNPGSVMTN WNSSLDTAAN SSRALSPVSY NDIPASPTMC 660
  661 AQVFNLPKST ESEHHQLTSQ QQNTTHYSSG SANTMTRSDG ATTVPMDNII TPTYAILNPI 720
  721 LVHEQTPNGT VPRKTSEELD SPDDVLPGPS LEEEEGDYAI IGGAAQKTDD ELLTRSIQSE 780
  781 MPTSSSTPKM KVSPRLNGFF SPTQKTTSSP AWSHPDTSPI PKSSSHRTQP NRRQDASDAD 840
  841 RLLMESIMSE MPKSRIISPR LAGTQQYLEP EPERRSHSKN EEADRRDAFT ASHEPSDHNG 900
  901 IDVARGSDWS PQQQLHRMES LESQASSEDS FGLTAEEPNS STSGAAANTM RFDDEIDASL 960
  961 PMDCVDDDDY DYTYDHFEDY EDEEDPDATQ FDDGVDAQLT IDCSMISSGS GSSQRNETTT1020
 1021 TSRDSKALAT STPKGSASSL PGVRQATRVS TNGKSRLPVP KTNGSLVDKN PKPIIASRRP1080
 1081 RLPPKPTLLK DKHYPEEDSI ENQTRDDTIY VNAPVVEAEQ ERIYMNALKQ QKNIEQSPSI1140
 1141 GNGSPIAKSA IVTPYNYQKP PFTGRNNGEM SNEKSVTPNP KQMLVTIV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Protein Overview: apr-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: