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Protein Overview: tut-1

General Information:
Name(s) found: tut-1 / CE17723 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00017928 locus:tut-1 Cytoplasmic tRNA 2-thiolation protein 1 status:Confirmed UniProt:O76365 protein_id:CCD62179.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 373 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: DNA repair [IMPLink to PubMed article]
    tRNA processing [IEALink to PubMed article]
    translation [IEALink to PubMed article]
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    ligase activity, forming carbon-nitrogen bonds [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKRRGPPPC QSGSGCSNPA KIRKAKDGAQ LCGPCFSRNF EDDVHEAIVN NKLFKRGERV  60
   61 AIGASGGKDS TVLAYVMKTL NDRHDYGLDL QLLSIDEGIK GYRDDSLLAV EKNRVEYGLP 120
  121 LTILSYRDLY GWTMDDIVAK IGKKNNCTFC GVFRRQALDR GAFKIGATKL VTGHNADDMA 180
  181 ETLLMNVLRG DIARLERCTN IVTGEEGDLP RAKPLKYCFE RDIVMYARTN QLEYFYTECI 240
  241 YAPNAYRGYA RKYVRDLEKV HPRAILDLIR SGEKVSVKKE VEMPTLKICE RCGYMTSQKL 300
  301 CKACLLIEGL NTGNTDLGVR KSKKSKKVTV EADELNKEGG CGSGGGGGGC GCAGAEDAAE 360
  361 NEETRQRLKD LQF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..373] PSI-BLAST 44.221849 GMP synthetase; GMP synthetase, central domain; GMP synthetase C-terminal dimerisation domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming carbon-nitrogen bonds
    		•  4.5241303311086 bayes_pls_golite062009
  • ligase activity
    		•  3.71561290487771 bayes_pls_golite062009
  • DNA binding
    		•  1.07561751049838 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.0681685328021 bayes_pls_golite062009
  • binding
    		•  0.915602461727954 bayes_pls_golite062009
  • catalytic activity
    		•  0.828867994386867 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.475055910258246 bayes_pls_golite062009
  • transferase activity
    		•  0.0776944314618701 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle