Protein Overview: let-418

General Information:
Name(s) found:	let-418 / CE17716 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00002637 locus:let-418 Protein let-418 status:Confirmed UniProt:G5EBZ4 protein_id:CCD62685.1 [WormBase] pir\|\|T34239 hypothetical protein F26F12.7 - Caenorhabditis elegans [NCBI NR] gi\|3294508\|gb\|AAC25894.1\| Lethal protein 418 [Caenorhabditis elegans] [NCBI NR] gi\|17562600\|ref\|NP_504523.1\| LEThal family member (let-418) [Caenorhabditis elegans] [NCBI NR] gi\|11095333\|gb\|AAG29838.1\| LET-418 [Caenorhabditis elegans] [NCBI NR] Protein let-418 OS=Caenorhabditis elegans GN=let-418 PE=1 SV=1 [Swiss-Prot] [wormpep67.fasta] CE17716 WBGene00002637 locus:let-418 DNA helicase status:Confirmed TR:Q19815 protein_id:AAC25894.1 [wormpep150.fasta] 17716 WBGene00002637 locus:let-418 DNA helicase status:Confirmed TR:Q19815 protein_id:AAC25894.1 [wormpep130-phg-ecoli-orf-rand.fasta] CHromoDomain protein, helicase Mi-2 like; chromatin remodeling protein, LEThal LET-418, abnormal Eversion of VuLva EVL-11 (209.2 kD) (let-418) [Caenorhabditis elegans]gi\|3294508\|gb\|AAC25894.1\| Lethal protein 418 [Caenorhabditis elegans]gi\|7499938\|pir\|\|T [nrdb_11152004_Chlamydomonas] locus:let-418 DNA helicase status:Confirmed TR:Q19815 protein_id:AAC25894.1 [wormpep115.fasta.reversed] CE17716 locus:let-418 DNA helicase status:Confirmed [wormpep80.hongbin] CE17716 WBGene00002637 locus:let-418 DNA helicase status:Confirmed UniProt:Q19815_CAEEL protein_id:AAC25894.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE17716 WBGene00002637 locus:let-418 DNA helicase status:Confirmed UniProt:Q19815_CAEEL protein_id:AAC25894.1\| [wormORF-contam.fasta] LEThal family member (let-418) [Caenorhabditis elegans] [nr-271106-contam.fasta] Lethal protein 418 [Caenorhabditis elegans] [nr-271106-contam.fasta] LET-418 [Caenorhabditis elegans] [nr-271106-contam.fasta] CE17716 WBGene00002637 locus:let-418 DNA helicase status:Confirmed UniProt:Q19815 protein_id:AAC25894.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE17716 WBGene00002637 locus:let-418 DNA helicase status:Confirmed UniProt:G5EBZ4 protein_id:CCD62685.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE17716 WBGene00002637 locus:let-418 status:Confirmed UniProt:G5EBZ4 protein_id:CCD62685.1 Protein let-418 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	1829 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] chromatin [IEA]
Biological Process:	nematode larval development [IMP] embryonic development ending in birth or egg hatching [IMP] chromatin assembly or disassembly [IEA] embryonic digestive tract morphogenesis [IGI] growth [IMP] reproduction [IMP]
Molecular Function:	nucleic acid binding [IEA] DNA binding [IEA] ATP binding [IEA] zinc ion binding [IEA] protein binding [IEA] ATP-dependent helicase activity [IEA] helicase activity [IEA] chromatin binding [IEA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTEEDPSLV DAEESMEEGS VTQDATEETE EEEEQEQGDE AGPSERKRSS RKKGGKGGKK  60
   61 GSKKSAAAAS KVEIPDPYNS TSEEVCAAIG LTDVEFDYDE EEFQGISNLK TFSSIIKPQI 120
  121 LEANPGTNVS KMYPMFQVKY KEYQDHMAAQ GKPVQKQARG SKTPAVSTPV IPPRSAPTKT 180
  181 RSARRKRRDS DAPDSDQEFE AFIKQQEQLE DDLVKDKEDA RIKRAAEREE KKKGALEAAR 240
  241 AAKKAKLEKG EEAENNDYCE ECKQDGELLL CDTCPRAYHT VCIDENMEEP PEGDWSCAHC 300
  301 IEHGPEVVKE EPAKQNDEFC KICKETENLL LCDSCVCSFH AYCIDPPLTE VPKEETWSCP 360
  361 RCETVKPEHK IEKILCWRWK EIPYPEPLEA GKEASSDDAM LKPPRKMEPR REREFFVKWK 420
  421 YLSYWQCSWV SEMLLEVHFR MLILLYWRKN DSDAPPEFEE SVTSRHHSDN DPYKLRERFY 480
  481 QYGIKPEWMQ IHRIINHQSY AKSQQDYLVK WKELSYDQAT WERDDSNIAN YEEAIIKYWQ 540
  541 HRESKLNEDI PKNVQKMIAK HREAKGLPPK EDEKKKKKRE KIDIRKKYEV QPDYVTETGG 600
  601 KLHPYQLEGL NWLRHCWSNG TDAILADEMG LGKTVQSLTF LYSLMKEGHC KGPFLIAAPL 660
  661 STIINWEREA EQWCPDFYVV TYVGLRDARV VLREHEFSFV EGAVRSGPKA SKMKTTENMK 720
  721 FHVLLTSYET INMDKTILSS IEWGALVVDE AHRLKNNQSL FFKNLNEYTI HYRVLLTGTP 780
  781 LQNNLEELFH LLNFLSKERF NQLEAFTAEF NEISKEDQIE KLHNLLGPHM LRRLKADVLT 840
  841 GMPSKSELIV RVELSAMQKK WYKNILTRNF DALNVKNGGT QMSLMNVLME LKKCCNHPYL 900
  901 FVKAELEAPK EKNGMYEGTA LIKNSGKFVL LQKMLRKLKD GGHRVLIFSQ MTRMLDIMED 960
  961 LCEYEGYRYE RIDGSIMGQM RQDAIDRYNA PGAQQFIFLL STRAGGLGIN LATADTVIIY1020
 1021 DSDWNPHNDI QAFSRAHRLG QKHKVMIYRF VTKKSVEEKI TSVAKKKMLL NHLVVRAGLG1080
 1081 GKEGKTMSKT ELDDVLRWGT EELFSEDLDA AEGEGSEKKG AAAQEIVWDD AAVDALLDRS1140
 1141 NKEETPAGED GEEKAEWQNE YLSSFKVASY QTKETEGQEE EEEEETEVIK EDEKEPDPDY1200
 1201 WEKLLKHHYE QDREIELQKL GKGKRVRKQI NYASENMGTD WSKQNQTQDD DDDNESYRGS1260
 1261 DNGDGLNSDE DDYDEKKKRR RDEEKMPPLM AKVNGQVEIL GFNPRQRKAF YGAVMRWGMP1320
 1321 PQDSHQSQWL VRDLRNKSEK VFRAYASLFM RHLCEPGADG HDTFNDGVPR EGLNRQHVLG1380
 1381 RIGLLSLVRR KVQEFEQYNG QWSMPEIQDE VLAKAANGSA QGSSRSTPKP KEEPKEEPME1440
 1441 KEDATETVNG ATSEPATDAE SEQNAPVDEP MDTDEAKEPK EEPIETEKPR AARPSFKFNI1500
 1501 CDGGFTELHS LWANEEKVAR NGKEYEIWYR RHDYWLLAGV VVHGYGRFQA NFNDIINDPR1560
 1561 FSVLNEPFKE VGAEATGSDI KAKFMQRRFK LIEQSLVIEE QLRRAAHANR HLQPDNVGPL1620
 1621 AQRFADLENI AESQANIAKE SSAGNRNANA VLHKTLVQLD EILSDMKADV SRLPSTFTQL1680
 1681 ATVTERLNMT ERQILSRLTT KDEDAIANRS VLPPPGPFVT PILRQQMDGI QPKFAALYSK1740
 1741 FMSENGERME EDEPVEAEEE EGVKQEPDDE TQDSAEAPPV LSAEVNSDDS NDVPSTSAAA1800
 1801 AVSSETAADA EPASAEDQAP TDEPEPMET

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: let-418

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: