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Protein Overview: icl-1

General Information:
Name(s) found: icl-1 / CE17360 [WormBase]
Description(s) found:
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  • WBGene00002046 locus:icln-1 status:Confirmed UniProt:G5EFZ5 protein_id:CAA92442.1 [WormBase]
  • pir||T18811 probable chloride channel protein - Caenorhabditis elegans [NCBI NR]
  • gi|71981813|ref|NP_001021287.1| ICLn ion channel homolog family member (icl-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|3881387|emb|CAA92573.1| C. elegans protein C01F6.8a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|3873822|emb|CAA92442.1| C. elegans protein C01F6.8a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_741476.1| ICLn ion channel homolog, nucleotide-sensitive chloride conductance regulator (22.9 kD) (icl-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|14581730|gb|AAK69381.1|AF202931_1 ICln1 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE17360 WBGene00002046 locus:icl-1 nucleotide-sensitive chloride ion channel status:Confirmed TR:Q17564 protein_id:CAA92573.1 [wormpep150.fasta]
  • 17360 WBGene00002046 locus:icl-1 status:Confirmed TR:Q17564 protein_id:CAA92573.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • ICLn ion channel homolog, nucleotide-sensitive chloride conductance regulator (22.9 kD) (icl-1) [Caenorhabditis elegans]gi|3881387|emb|CAA92573.1| Hypothetical protein C01F6.8a [Caenorhabditis elegans]gi|3873822|emb|CAA92442.1| Hypothetical protein C01F [nrdb_11152004_Chlamydomonas]
  • CE17360 WBGene00002046 locus:icl-1 status:Confirmed TR:Q17564 protein_id:CAA92573.1 [wormpep132.fasta]
  • 17360 WBGene00002046 locus:icl-1 nucleotide-sensitive chloride ion channel status:Confirmed TR:Q17564 protein_id:CAA92573.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:icl-1 status:Confirmed TR:Q17564 protein_id:CAA92573.1 [wormpep115.fasta.reversed]
  • CE17360 status:Confirmed TR:Q17564 protein_id:CAA92573.1 [wormpep80.hongbin]
  • CE17360 WBGene00002046 locus:icl-1 nucleotide-sensitive chloride ion channel status:Confirmed UniProt:Q17564_CAEEL protein_id:CAA92573.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE17360 WBGene00002046 locus:icl-1 nucleotide-sensitive chloride ion channel status:Confirmed UniProt:Q17564_CAEEL protein_id:CAA92573.1| [wormORF-contam.fasta]
  • ICln1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein C01F6.8a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • ICLn ion channel homolog family member (icl-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE17360 WBGene00002046 locus:icl-1 nucleotide-sensitive chloride ion channel status:Confirmed UniProt:Q17564 protein_id:CAA92573.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE17360 WBGene00002046 locus:icln-1 nucleotide-sensitive chloride ion channel status:Confirmed UniProt:G5EFZ5 protein_id:CAA92442.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE17360 WBGene00002046 locus:icln-1 status:Confirmed UniProt:G5EFZ5 protein_id:CAA92442.1 [wormpep246-ecoli-contam.fasta]
  • Isoform of G5EG22, ICLN (ICLn) ion channel homolog OS=Caenorhabditis elegans GN=icln-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 205 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    chloride transport [IEALink to PubMed article]
    cell volume homeostasis [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILTEVSQPT EGIKLATTNV QAFFKIDSLG NGTLYITDSA VIWISSAAGT KGFSVAYPAI  60
   61 VLHAISTDVS VFPSEHIFVM VDQRKSGLEL AAAELEDEES DDDEEEPALE IRFVPDDKDS 120
  121 LSQIYHQIAV GQEENPEEDD PMYDDEEEEM EEEMGDDGQG QSGQWFTADN IDHMQMSEEG 180
  181 LANMQRIFGR GDQHQHHHNE DESME

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..205] PSI-BLAST 44.154902 Solution structure of ICLN, a multifunctional protein involved in regulatory mechanisms as different as cell volume regulation and rna splicing


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle