YRC Public Data Repository - Protein Structure Prediction

Protein:	icl-1
Organism:	Caenorhabditis elegans
Length:	205 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for icl-1.

Description	E-value	Query Range	Subject Range
gi\|39586447, gi\|... - gi\|39586447\|emb\|CAE74106.1\| Hypothetical protein CBG21766 [Caenorhabditis briggsae], gi\|187022360\|em... gi\|157755327 - gi\|157755327\|ref\|XP_001670007.1\| Hypothetical protein CBG21766 [Caenorhabditis briggsae AF16]	233.0	[0..1]	[205..3]
icl-1 - nucleotide-sensitive chloride ion channel status:Confirmed UniProt:Q965E1 protein_id:CAD21675.1	231.0	[0..1]	[205..1]
gi\|19263324, gi\|... - gi\|74141910\|dbj\|BAE41022.1\| unnamed protein product [Mus musculus], gi\|26327689\|dbj\|BAC27588.1\| unna...	215.0	[0..3]	[189..9]
gi\|431451, gi\|38... - pir\|\|B53014 chloride channel protein I-Cln - rat, gi\|431451\|gb\|AAC37642.1\| regulatory protein, gi\|38...	214.0	[0..3]	[193..9]
gi\|2197127 - gi\|2197127\|gb\|AAC48778.1\| swelling-induced chloride conductance regulatory protein pIcIn [Oryctolagu...	212.0	[0..3]	[189..4]
gi\|114639484 - gi\|114639484\|ref\|XP_001175048.1\| PREDICTED: chloride channel, nucleotide-sensitive, 1A isoform 1 [Pa...	211.0	[0..3]	[189..4]

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Predicted Domain #1

Region A:
Residues: [1-205]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILTEVSQPT EGIKLATTNV QAFFKIDSLG NGTLYITDSA VIWISSAAGT KGFSVAYPAI  60
   61 VLHAISTDVS VFPSEHIFVM VDQRKSGLEL AAAELEDEES DDDEEEPALE IRFVPDDKDS 120
  121 LSQIYHQIAV GQEENPEEDD PMYDDEEEEM EEEMGDDGQG QSGQWFTADN IDHMQMSEEG 180
  181 LANMQRIFGR GDQHQHHHNE DESME

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.154902
Match:	1zyiA
Description:	Solution structure of ICLN, a multifunctional protein involved in regulatory mechanisms as different as cell volume regulation and rna splicing
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits