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Protein Overview: isp-1

General Information:
Name(s) found: isp-1 / CE17071 [WormBase]
Description(s) found:
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  • WBGene00002162 locus:isp-1 Cytochrome b-c1 complex subunit Rieske, mitochondrial status:Confirmed UniProt:O44512 protein_id:CCD61411.1 [WormBase]
  • pir||T32640 ubiquinol-cytochrome-c reductase (EC 1.10.2.2) Rieske iron-sulfur protein [similarity] - Caenorhabditis elegans [NCBI NR]
  • gi|2702451|gb|AAB92071.1| Iron-sulfur protein protein 1 [Caenorhabditis elegans] [NCBI NR]
  • gi|17540418|ref|NP_501361.1| Iron-Sulfur Protein family member (isp-1) [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE17071 WBGene00002162 locus:isp-1 ubiquinol-cytochrome C reductase status:Confirmed TR:O44512 protein_id:AAB92071.1 [wormpep150.fasta]
  • 17071 WBGene00002162 locus:isp-1 ubiquinol-cytochrome C reductase status:Confirmed TR:O44512 protein_id:AAB92071.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • iron Sulfur Protein (29.7 kD) (isp-1) [Caenorhabditis elegans]gi|2702451|gb|AAB92071.1| Iron-sulfur protein protein 1 [Caenorhabditis elegans]gi|7503274|pir||T32640 ubiquinol-cytochrome-c reductase (EC 1.10.2.2) Rieske iron-sulfur protein [similarity] - [nrdb_11152004_Chlamydomonas]
  • locus:isp-1 ubiquinol-cytochrome C reductase status:Confirmed TR:O44512 protein_id:AAB92071.1 [wormpep115.fasta.reversed]
  • CE17071 locus:isp-1 ubiquinol-cytochrome C reductase status:Confirmed TR:O44512 protein_id:AAB92071.1 [wormpep80.hongbin]
  • CE17071 WBGene00002162 locus:isp-1 ubiquinol-cytochrome C reductase status:Confirmed UniProt:O44512_CAEEL protein_id:AAB92071.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE17071 WBGene00002162 locus:isp-1 ubiquinol-cytochrome C reductase status:Confirmed UniProt:O44512_CAEEL protein_id:AAB92071.1| [wormORF-contam.fasta]
  • Iron-Sulfur Protein family member (isp-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Iron-sulfur protein protein 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE17071 WBGene00002162 locus:isp-1 ubiquinol-cytochrome C reductase status:Confirmed UniProt:O44512 protein_id:AAB92071.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE17071 WBGene00002162 locus:isp-1 ubiquinol-cytochrome C reductase status:Confirmed UniProt:O44512 protein_id:CCD61411.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE17071 WBGene00002162 locus:isp-1 status:Confirmed UniProt:O44512 protein_id:CCD61411.1 Cytochrome b-c1 complex subunit Rieske, mitochondrial [wormpep246-ecoli-contam.fasta]
  • Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Caenorhabditis elegans GN=isp-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 276 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: electron transport [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    mitochondrial electron transport, ubiquinol to cytochrome c [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: ubiquinol-cytochrome-c reductase activity [IEALink to PubMed article]
    oxidoreductase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASLARSGGF AVKVISGSQQ HVNFVAATPA ADNVAAFRDV PAEFSTAEAR QAAVSHSTGG  60
   61 VFTNGLAVKG INVTSRRLAH TDVTFPDMSN YRRDSTKNTQ VPARDTEDQR RALPTALYYG 120
  121 AGGVLSLWAG KEVVQTLVSY KAMAADQRAL ASIEINMADI PEGKTKTFEW RGKPVFVKHR 180
  181 TKAEIAKEKA VPVADLRHPQ HDDERVQKDE WSVVIGVCTH LGCVPIADAG DYGGYYCPCH 240
  241 GSHYDASGRI RKGPAPLNLH VPAYSFKDAT IVIGSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..276] PSI-BLAST 47.221849 ISP subunit of the mitochondrial cytochrome bc1-complex, watersoluble domain; Iron-sulfur subunit (ISP) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane region

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquinol-cytochrome-c reductase activity
    		•  12.5243667017255 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
    		•  12.5243667017255 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors
    		•  9.125468664417 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  6.56410033542443 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  6.40889163290296 bayes_pls_golite062009
  • oxidoreductase activity
    		•  6.05060612159037 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  5.79350583896014 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  5.52425708699797 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  5.31511996363681 bayes_pls_golite062009
  • electron carrier activity
    		•  5.20213585732279 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.88364619884033 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  4.66567624087954 bayes_pls_golite062009
  • binding
    		•  0.859614464562991 bayes_pls_golite062009
  • catalytic activity
    		•  0.746741393172769 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  0.71220774812099 bayes_pls_golite062009
  • metal cluster binding
    		•  0.71220774812099 bayes_pls_golite062009
  • protein binding
    		•  0.400602154675453 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle