Protein Overview: isp-1

General Information:
Name(s) found:	isp-1 / CE17071 [WormBase]
Description(s) found: Found 19 descriptions. SHOW ALL	WBGene00002162 locus:isp-1 Cytochrome b-c1 complex subunit Rieske, mitochondrial status:Confirmed UniProt:O44512 protein_id:CCD61411.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	276 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA]
Biological Process:	electron transport [IEA] embryonic development ending in birth or egg hatching [IMP ] mitochondrial electron transport, ubiquinol to cytochrome c [IMP] reproduction [IMP]
Molecular Function:	ubiquinol-cytochrome-c reductase activity [IEA] oxidoreductase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASLARSGGF AVKVISGSQQ HVNFVAATPA ADNVAAFRDV PAEFSTAEAR QAAVSHSTGG  60
   61 VFTNGLAVKG INVTSRRLAH TDVTFPDMSN YRRDSTKNTQ VPARDTEDQR RALPTALYYG 120
  121 AGGVLSLWAG KEVVQTLVSY KAMAADQRAL ASIEINMADI PEGKTKTFEW RGKPVFVKHR 180
  181 TKAEIAKEKA VPVADLRHPQ HDDERVQKDE WSVVIGVCTH LGCVPIADAG DYGGYYCPCH 240
  241 GSHYDASGRI RKGPAPLNLH VPAYSFKDAT IVIGSS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..276]	PSI-BLAST	47.221849	ISP subunit of the mitochondrial cytochrome bc1-complex, watersoluble domain; Iron-sulfur subunit (ISP) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane region

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
ubiquinol-cytochrome-c reductase activity	12.5243667017255	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	12.5243667017255	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors	9.125468664417	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	6.56410033542443	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	6.40889163290296	bayes_pls_golite062009
oxidoreductase activity	6.05060612159037	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	5.79350583896014	bayes_pls_golite062009
cation transmembrane transporter activity	5.52425708699797	bayes_pls_golite062009
ion transmembrane transporter activity	5.31511996363681	bayes_pls_golite062009
electron carrier activity	5.20213585732279	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	4.88364619884033	bayes_pls_golite062009
substrate-specific transporter activity	4.66567624087954	bayes_pls_golite062009
binding	0.859614464562991	bayes_pls_golite062009
catalytic activity	0.746741393172769	bayes_pls_golite062009
iron-sulfur cluster binding	0.71220774812099	bayes_pls_golite062009
metal cluster binding	0.71220774812099	bayes_pls_golite062009
protein binding	0.400602154675453	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.90

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle