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Protein Overview: ubc-12

General Information:
Name(s) found: ubc-12 / CE16309 [WormBase]
Description(s) found:
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  • WBGene00006707 locus:ubc-12 NEDD8-conjugating enzyme ubc-12 status:Confirmed UniProt:Q9XVK5 protein_id:CAB03238.1 [WormBase]
  • pir||T24069 hypothetical protein R09B3.4 - Caenorhabditis elegans [NCBI NR]
  • gi|75028706|sp|Q9XVK5.1|UBC12_CAEEL RecName: Full=NEDD8-conjugating enzyme ubc-12; AltName: Full=NEDD8 protein ligase; AltName: Full=NEDD8 carrier protein; AltName: Full=Ubiquitin-conjugating enzyme E2 12 [NCBI NR]
  • gi|3879017|emb|CAB03238.1| C. elegans protein R09B3.4, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17508589|ref|NP_493024.1| UBiquitin Conjugating enzyme family member (ubc-12) [Caenorhabditis elegans] [NCBI NR]
  • NEDD8-conjugating enzyme ubc-12 OS=Caenorhabditis elegans GN=ubc-12 PE=2 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE16309 WBGene00006707 locus:ubc-12 Ubiquitin-conjugating enzymes status:Partially_confirmed TR:Q9XVK5 protein_id:CAB03238.1 [wormpep150.fasta]
  • 16309 WBGene00006707 locus:ubc-12 Ubiquitin-conjugating enzymes status:Partially_confirmed TR:Q9XVK5 protein_id:CAB03238.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • ubiquitin conjugating enzyme (ubc-12) [Caenorhabditis elegans]gi|3879017|emb|CAB03238.1| Hypothetical protein R09B3.4 [Caenorhabditis elegans]gi|7506502|pir||T24069 hypothetical protein R09B3.4 - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas]
  • locus:ubc-12 Ubiquitin-conjugating enzymes status:Partially_confirmed TR:Q9XVK5 protein_id:CAB03238.1 [wormpep115.fasta.reversed]
  • CE16309 locus:ubc-12 Ubiquitin-conjugating enzymes status:Partially_confirmed TR:Q9XVK5 protein_id:CAB03238.1 [wormpep80.hongbin]
  • CE16309 WBGene00006707 locus:ubc-12 Ubiquitin-conjugating enzymes status:Confirmed UniProt:UBC12_CAEEL protein_id:CAB03238.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE16309 WBGene00006707 locus:ubc-12 Ubiquitin-conjugating enzymes status:Confirmed UniProt:UBC12_CAEEL protein_id:CAB03238.1| [wormORF-contam.fasta]
  • CE16309 WBGene00006707 locus:ubc-12 Ubiquitin-conjugating enzymes status:Partially_confirmed SW:Q9XVK5 protein_id:CAB03238.1 [wormpep160-contam.fasta]
  • UBiquitin Conjugating enzyme family member (ubc-12) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein R09B3.4 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • NEDD8-conjugating enzyme ubc-12 (NEDD8 protein ligase) (NEDD8 carrier protein) (Ubiquitin-conjugating enzyme E2 12) [nr-271106-contam.fasta]
  • CE16309 WBGene00006707 locus:ubc-12 Ubiquitin-conjugating enzymes status:Confirmed SW:Q9XVK5 protein_id:CAB03238.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • CE16309 WBGene00006707 locus:ubc-12 Ubiquitin-conjugating enzymes status:Confirmed UniProt:Q9XVK5 protein_id:CAB03238.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE16309 WBGene00006707 locus:ubc-12 status:Confirmed UniProt:Q9XVK5 protein_id:CAB03238.1 NEDD8-conjugating enzyme ubc-12 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 180 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic cleavage [IMPLink to PubMed article]
    DNA repair [IMPLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    determination of adult lifespan [IMPLink to PubMed article]
    protein modification process [IEALink to PubMed article]
    cytokinesis [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    ubiquitin cycle [IEALink to PubMed article]
    Molecular Function: small conjugating protein ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFNLQKRING NNEDGRYLET RIAVRDKLLA QELQQLETAL RDQKQKLWHL EVPSTSCLHE  60
   61 LELTVTPQEG IYRGGKFRFK ITVPPEYNNV PPVVKCLTKV WHPNINEDGS ICLSILRQNS 120
  121 LDQYGWRPTR NLTDVVHGLV SLFNDLMDFN DALNIQAAQM WSQNRESFNH RVREYISRYC 180
  181

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..180] PSI-BLAST 37.69897 No description for 2ediA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle