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Protein Overview: unc-115

General Information:
Name(s) found: unc-115 / CE15759 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00006839 locus:unc-115 status:Confirmed UniProt:Q19240 protein_id:CAA90057.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 625 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: negative regulation of multicellular organism growth [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    cytoskeleton organization [IEALink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    Molecular Function: actin filament binding [IDALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    actin binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKCDVCRK KCSGDVLKAN DKYFHINCFQ CKKCGRNLGE TGFYTTPENA YLCPDDFRAV  60
   61 SKEITVKTTT QQAHASSSSA ATPKSPEKSN GTTDVSSSGA ANATLQQISP LGSPTTCAAC 120
  121 DQALHSGQVL LALGLSWHVY CFKCSECSAV LHGEYMSHHG KPLCLRDYNE KFGVKCYECE 180
  181 KFIAGKVLQA GGYKFHPTCA RCSRCGSHFG DGEEMYMQGD EIWHPSCEHA RTTENIAPTG 240
  241 RAATLSRNEP KYQSTFGQHQ AYMYLLPEVE QTYLRHPVMN AKEPNAPQYH VPQGPIKIRK 300
  301 SRMSMLKTGM QRLTEDLEKN IPRPKSPHMD NEEPIELAHY PAAHVPDPDT LPAIEREDFP 360
  361 APQFPYAVEE LKRRLSTSSV ENEISDDEYS ESDKVDEDKL RKTVETLEKY NDSSIAHVIR 420
  421 QNIEDSHKKQ RLPLHWDPRN ASRTPSGKKM PHLKFRYDVP INASPSRHLN RPRPWVVWQG 480
  481 GERDQGNNTL PCFHIPEDSR ANTLRAATLP TEFGQNLSLE NLDTTISSHY SEHSTTESGT 540
  541 AGGPRSAGGA VLRSSLPDMS KPAKQYDLLF LQTTNSDLPE DVDRQHLERH LPRDQFEEIF 600
  601 KMSLIEFYKL PEWKRINLKR KHKLF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..181] PSI-BLAST 48.045757 No description for 2i13A was found.
    2 View Details [182..224] FFAS03 2.87 Solution Structure of the LIM Domain of the Human Actin Binding LIM Protein 2
    3 View Details [225..326] PSI-BLAST 13.69897 ZIF268
    4 View Details [327..465] PSI-BLAST 10.0 Solution structure of the first and second zf-C2H2 domain of Zinc finger protein 435
    5 View Details [466..544] deduced N/A No confident structure predictions are available.
    6 View Details [545..625] PSI-BLAST 25.69897 Solution structure of the Villin headpiece domain of human actin-binding LIM protein homologue (KIAA0843 protein)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.33031501809283 bayes_pls_golite062009
  • protein binding
    		•  0.484915054040372 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.340288079661743 bayes_pls_golite062009
  • DNA binding
    		•  0.00134487825101615 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  1.5693324142242 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.20084827450202 bayes_pls_golite062009
  • DNA binding
    		•  1.11228868978256 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.10067326005752 bayes_pls_golite062009
  • transcription factor activity
    		•  0.33874886911135 bayes_pls_golite062009
  • protein binding
    		•  0.186544761618633 bayes_pls_golite062009
    5 No functions predicted.
    6
    Term Confidence Notes
  • binding
    		•  0.890394134199723 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle