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Protein Overview: cdc-37

General Information:
Name(s) found: cdc-37 / CE14726 [WormBase]
Description(s) found:
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  • WBGene00021097 locus:cdc-37 Probable Hsp90 co-chaperone cdc37 status:Confirmed UniProt:O02108 protein_id:CCD63937.1 [WormBase]
  • pir||T34050 hypothetical protein W08F4.8 - Caenorhabditis elegans [NCBI NR]
  • gi|21541993|sp|O02108.1|CDC37_CAEEL RecName: Full=Probable Hsp90 co-chaperone cdc37; AltName: Full=Hsp90 chaperone protein kinase-targeting subunit; AltName: Full=Cell division cycle-related protein 37 [NCBI NR]
  • gi|1947029|gb|AAC71172.1| Hypothetical protein W08F4.8a [Caenorhabditis elegans] [NCBI NR]
  • gi|17536793|ref|NP_493761.1| W08F4.8 [Caenorhabditis elegans] [NCBI NR]
  • gi|115532610|ref|NP_001040820.1| Cell Division Cycle related family member (cdc-37) [Caenorhabditis elegans] [NCBI NR]
  • Probable Hsp90 co-chaperone cdc37 OS=Caenorhabditis elegans GN=cdc-37 PE=3 SV=1 [Swiss-Prot]
  • (O02108) Probable Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) [Swiss-Prot]
  • [wormpep67.fasta]
  • CE14726 WBGene00021097 status:Confirmed SW:O02108 protein_id:AAC71172.1 [wormpep150.fasta]
  • 14726 WBGene00021097 status:Confirmed SW:O02108 protein_id:AAC71172.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • cdc37 (42.7 kD) (2A868) [Caenorhabditis elegans]gi|1947029|gb|AAC71172.1| Hypothetical protein W08F4.8 [Caenorhabditis elegans]gi|7509147|pir||T34050 hypothetical protein W08F4.8 - Caenorhabditis elegansgi|21541993|sp|O02108|CC37_CAEEL Probable Hsp90 c [nrdb_11152004_Chlamydomonas]
  • status:Confirmed SW:O02108 protein_id:AAC71172.1 [wormpep115.fasta.reversed]
  • CE14726 status:Confirmed TR:O02108 protein_id:AAC71172.1 [wormpep80.hongbin]
  • CE14726 WBGene00021097 locus:cdc-37 status:Confirmed UniProt:O02108 protein_id:AAC71172.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE14726 WBGene00021097 locus:cdc-37 status:Confirmed UniProt:O02108 protein_id:AAC71172.1| [wormORF-contam.fasta]
  • CE14726 WBGene00021097 locus:cdc-37 status:Confirmed SW:O02108 protein_id:AAC71172.1 [wormpep160-contam.fasta]
  • Cell Division Cycle related family member (cdc-37) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Probable Hsp90 co-chaperone cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (Cell division cycle-related protein 37) [nr-271106-contam.fasta]
  • Hypothetical protein W08F4.8a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE14726 WBGene00021097 locus:cdc-37 status:Confirmed UniProt:O02108 protein_id:CCD63937.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE14726 WBGene00021097 locus:cdc-37 status:Confirmed UniProt:O02108 protein_id:CCD63937.1 Probable Hsp90 co-chaperone cdc37 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 370 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIDYSKWKD IEVSDDEDDT HPNIDTPSLF RWRHQARLER MAEKKMEQEK IDKEKGTTSK  60
   61 KMEELEKKLA AADVTDKSDI QKQIDEVKAQ EEAWRKKEAE LEEKERLEPW NVDTIGHEAF 120
  121 STSRINKITE KKPQAPKTDE EDTHAMSTFF ETHESLLEKM AVLKNGAKST ELFLAEHPHM 180
  181 ASEYTANWLT IEALNAAIDF NEEKMKTMAE QCIIIQYLLE LSKSLNAVAT NTTVQKQFFK 240
  241 KFEAAEPVYM KHYQDEVKAF EDRLRTRAQT KRDAAMEEAE AEEKAERMKS APGGIDPQEV 300
  301 FEQLPEEMRK CFEAHDIEAL KGVAQKMDEE VFKYHFDRCI ASGLWVPGKA DDDDDDEEAA 360
  361 PAEEEPTTSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..139] Pfam 56.040959 No description for PF03234.5 was found. No confident structure predictions are available.
    2 View Details [140..370] PSI-BLAST 25.154902 Complex of Hsp90 and P50

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.63059449218992 bayes_pls_golite062009
  • protein binding
    		•  0.967371813449539 bayes_pls_golite062009
  • unfolded protein binding
    		•  0.68193901105298 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle