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Protein Overview: gld-1

General Information:
Name(s) found: gld-1 / CE14096 [WormBase]
Description(s) found:
Found 24 descriptions.
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  • WBGene00001595 locus:gld-1 Female germline-specific tumor suppressor gld-1 status:Confirmed UniProt:Q17339 protein_id:CAB03417.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 463 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    P granule [IDALink to PubMed article]
    cytosol [IDALink to PubMed articleLink to PubMed article]
    Biological Process: oocyte construction [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    germline cell cycle switching, mitotic to meiotic cell cycle [IMPLink to PubMed article]
    regulation of meiosis [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    gamete generation [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    masculinization of hermaphrodite soma [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    masculinization of hermaphroditic germ-line [IMPLink to PubMed article]
    Molecular Function: RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSCTTPTYG VSTQLESQSS ESPSRSSVMT PTSLDGDNSP RKRFPIIDNV PADRWPSTRR  60
   61 DGWSSVRAPP PARLTLSTNN RHIMSPISSA YSQTPNSLLS PAMFNPKSRS IFSPTLPATP 120
  121 MSYGKSSMDK SLFSPTATEP IEVEATVEYL ADLVKEKKHL TLFPHMFSNV ERLLDDEIGR 180
  181 VRVALFQTEF PRVELPEPAG DMISITEKIY VPKNEYPDYN FVGRILGPRG MTAKQLEQDT 240
  241 GCKIMVRGKG SMRDKSKESA HRGKANWEHL EDDLHVLVQC EDTENRVHIK LQAALEQVKK 300
  301 LLIPAPEGTD ELKRKQLMEL AIINGTYRPM KSPNPARVMT AVPLLSPTPL RSSGPVLMSP 360
  361 TPGSGLPSTT FGGSILSPTL TASNLLGSNV FDYSLLSPSM FDSFSSLQLA SDLTFPKYPT 420
  421 TTSFVNSFPG LFTSASSFAN QTNTNVSPSG ASPSASSVNN TSF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130] deduced N/A No confident structure predictions are available.
    2 View Details [131..192] MSA 2.135991 View MSA. No confident structure predictions are available.
    3 View Details [193..356] PSI-BLAST 51.69897 Solution structure of the KH-QUA2 region of the Xenopus STAR-GSG Quaking protein.
    4 View Details [357..463] MSA 12.156997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.12000404411947 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.43118614950511 bayes_pls_golite062009
  • mRNA binding
    		•  0.59869578469175 bayes_pls_golite062009
  • protein binding
    		•  0.446932489882167 bayes_pls_golite062009
  • RNA binding
    		•  0.332356996824116 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle