Protein Overview: act-3

General Information:
Name(s) found:	act-3 / CE13148 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00000063 locus:act-1 Actin-1 status:Confirmed UniProt:P0DM41 protein_id:CAB04678.1 [WormBase] gi\|6624\|emb\|CAA34717.1\| actin [Caenorhabditis elegans] [NCBI NR] gi\|3879477\|emb\|CAB04678.1\| C. elegans protein T04C12.6, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|3879475\|emb\|CAB04676.1\| C. elegans protein T04C12.4, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] pir\|\|S16710 actin 1 and actin 3 - Caenorhabditis elegans [NCBI NR] gi\|17563822\|ref\|NP_505819.1\| ACTin family member (act-1) [Caenorhabditis elegans] [NCBI NR] gi\|17563820\|ref\|NP_505817.1\| ACTin family member (act-3) [Caenorhabditis elegans] [NCBI NR] gi\|113291\|sp\|P10983.2\|ACT1_CAEEL RecName: Full=Actin-1/3 [NCBI NR] Actin-3 OS=Caenorhabditis elegans GN=act-3 PE=1 SV=1 [Swiss-Prot] Actin-1 OS=Caenorhabditis elegans GN=act-1 PE=1 SV=1 [Swiss-Prot] [wormpep67.fasta] CE13148 WBGene00000063 locus:act-1 actin status:Confirmed SW:P10983 protein_id:CAB04678.1 [wormpep150.fasta] CE13148 WBGene00000065 locus:act-3 actin status:Confirmed SW:P10983 protein_id:CAB04676.1 [wormpep150.fasta] 13148 WBGene00000063 locus:act-1 actin status:Confirmed SW:P10983 protein_id:CAB04678.1 [wormpep130-phg-ecoli-orf-rand.fasta] 13148 WBGene00000065 locus:act-3 actin status:Confirmed SW:P10983 protein_id:CAB04676.1 [wormpep130-phg-ecoli-orf-rand.fasta] UNCoordinated locomotion UNC-92, actin (41.8 kD) (act-1) [Caenorhabditis elegans]gi\|17563820\|ref\|NP_505817.1\| actin (41.8 kD) (act-3) [Caenorhabditis elegans]gi\|3879477\|emb\|CAB04678.1\| Hypothetical protein T04C12.6 [Caenorhabditis elegans]gi\|3879475\|em [nrdb_11152004_Chlamydomonas] locus:act-1 actin status:Confirmed SW:P10983 protein_id:CAB04678.1 [wormpep115.fasta.reversed] CE13148 locus:act-3 actin status:Partially_confirmed SW:P10983 protein_id:CAB04676.1 [wormpep80.hongbin] CE13148 locus:act-1 actin status:Confirmed SW:P10983 protein_id:CAB04678.1 [wormpep80.hongbin] CE13148 WBGene00000065 locus:act-3 actin status:Confirmed UniProt:P10983 protein_id:CAB04676.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE13148 WBGene00000063 locus:act-1 actin status:Confirmed UniProt:P10983 protein_id:CAB04678.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE13148 WBGene00000063 locus:act-1 actin status:Confirmed UniProt:P10983 protein_id:CAB04678.1\| [wormORF-contam.fasta] CE13148 WBGene00000065 locus:act-3 actin status:Confirmed UniProt:P10983 protein_id:CAB04676.1\| [wormORF-contam.fasta] actin [Caenorhabditis elegans] [nr-271106-contam.fasta] Actin-1/3 [nr-271106-contam.fasta] Hypothetical protein T04C12.4 [Caenorhabditis elegans] [nr-271106-contam.fasta] T04C12.6 [Caenorhabditis elegans] [nr-271106-contam.fasta] T04C12.4 [Caenorhabditis elegans] [nr-271106-contam.fasta] Hypothetical protein T04C12.6 [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE13148 WBGene00000065 locus:act-3 status:Confirmed UniProt:P0DM42 protein_id:CAB04676.1 Actin-3 [wormpep246-ecoli-contam.fasta] CE13148 WBGene00000063 locus:act-1 status:Confirmed UniProt:P0DM41 protein_id:CAB04678.1 Actin-1 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	376 amino acids
Gene Ontology:
Cellular Component:	cytoskeleton [ISS]
Biological Process:	embryonic development [IGI] embryonic cleavage [IMP] muscle organ development [IMP] actin filament-based process [IGI] hermaphrodite genitalia development [IMP ] nematode larval development [IMP] cytokinesis after mitosis [IGI] embryonic development ending in birth or egg hatching [IMP] cytokinesis [IMP] actin cytoskeleton organization [IGI ][IMP ] reproduction [IMP ] growth [IMP]
Molecular Function:	ATP binding [IEA] protein binding [IEA] structural constituent of cytoskeleton [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCDDEVAALV VDNGSGMCKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGDEAQ  60
   61 SKRGILTLKY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM 120
  121 TQIMFETFNT PAMYVAIQAV LSLYASGRTT GVVLDSGDGV THTVPIYEGY ALPHAILRLD 180
  181 LAGRDLTDYL MKILTERGYS FTTTAEREIV RDIKEKLCYV ALDFEQEMAT AASSSSLEKS 240
  241 YELPDGQVIT VGNERFRCPE AMFQPSFLGM ESAGIHETSY NSIMKCDIDI RKDLYANTVL 300
  301 SGGTTMYPGI ADRMQKEITA LAPSTMKIKI IAPPERKYSV WIGGSILASL STFQQMWISK 360
  361 QEYDESGPSI VHRKCF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	None Entered	No Comments	Cheeseman, I.M., et al. (2004)
View Run	knl-1	No Comments	Cheeseman, I.M., et al. (2004)
View Run	None Entered	No Comments	Cheeseman, I.M., et al. (2004)
View Run	hcp-1	hcp1 IP from december2004	Cheeseman, I.M., et al. (2005)
View Run	hcp-2	hcp2 ip from december	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..376]	PSI-BLAST	156.0	Actin

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.76

Protein Overview: act-3

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: