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Protein Overview: pgk-1

General Information:
Name(s) found: pgk-1 / CE13100 [WormBase]
Description(s) found:
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  • WBGene00020185 locus:pgk-1 Probable phosphoglycerate kinase status:Confirmed UniProt:P91427 protein_id:CCD67788.1 [WormBase]
  • pir||T29198 hypothetical protein T03F1.3 - Caenorhabditis elegans [NCBI NR]
  • gi|2499493|sp|P91427.1|PGK_CAEEL RecName: Full=Probable phosphoglycerate kinase [NCBI NR]
  • gi|1825605|gb|AAB42230.1| Phosphoglycerate kinase protein 1 [Caenorhabditis elegans] [NCBI NR]
  • gi|17508823|ref|NP_491245.1| PhosphoGlycerate Kinase family member (pgk-1) [Caenorhabditis elegans] [NCBI NR]
  • Probable phosphoglycerate kinase OS=Caenorhabditis elegans GN=pgk-1 PE=3 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE13100 WBGene00020185 phosphoglycerate kinase status:Confirmed SW:P91427 protein_id:AAB42230.1 [wormpep150.fasta]
  • 13100 WBGene00020185 phosphoglycerate kinase status:Confirmed SW:P91427 protein_id:AAB42230.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • phosphoglycerate kinase (44.1 kD) (1E435) [Caenorhabditis elegans]gi|1825605|gb|AAB42230.1| Hypothetical protein T03F1.3 [Caenorhabditis elegans]gi|7507007|pir||T29198 hypothetical protein T03F1.3 - Caenorhabditis elegansgi|2499493|sp|P91427|PGK_CAEEL [nrdb_11152004_Chlamydomonas]
  • phosphoglycerate kinase status:Confirmed SW:P91427 protein_id:AAB42230.1 [wormpep115.fasta.reversed]
  • CE13100 phosphoglycerate kinase status:Confirmed SW:P91427 protein_id:AAB42230.1 [wormpep80.hongbin]
  • CE13100 WBGene00020185 locus:pgk-1 phosphoglycerate kinase status:Confirmed UniProt:PGK_CAEEL protein_id:AAB42230.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE13100 WBGene00020185 locus:pgk-1 phosphoglycerate kinase status:Confirmed UniProt:PGK_CAEEL protein_id:AAB42230.1| [wormORF-contam.fasta]
  • CE13100 WBGene00020185 locus:pgk-1 phosphoglycerate kinase status:Confirmed SW:P91427 protein_id:AAB42230.1 [wormpep160-contam.fasta]
  • Probable phosphoglycerate kinase [nr-271106-contam.fasta]
  • PhosphoGlycerate Kinase family member (pgk-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein T03F1.3 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE13100 WBGene00020185 locus:pgk-1 phosphoglycerate kinase status:Confirmed UniProt:P91427 protein_id:AAB42230.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE13100 WBGene00020185 locus:pgk-1 phosphoglycerate kinase status:Confirmed UniProt:P91427 protein_id:CCD67788.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE13100 WBGene00020185 locus:pgk-1 status:Confirmed UniProt:P91427 protein_id:CCD67788.1 Probable phosphoglycerate kinase [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 417 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: glycolysis [IEALink to PubMed article]
    Molecular Function: phosphoglycerate kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLNKLAID QLNLAGKRVL IRVDFNVPLK DGKITNNQRI AAAVPTIQHA LSNGAKSVVL  60
   61 MSHLGRPDGR RQDKYTLKPV AEELKALLKK DVLFLDDCVG SEVEAACADP APGSVILLEN 120
  121 LRYHLEEEGK GVDASGAKVK ADSAAVKKFR ESLTKLGDIY VNDAFGTAHR AHSSMVGVEH 180
  181 SQRASGFLLK NELSYFSKAL DNPARPFLAI LGGAKVADKI QLIKNLLDKV NEMIIGGGMA 240
  241 YTFLKVAQGV KIGNSLYDEE GAKIVNELLE AAKAKGVQIH LPVDFVIADK FAEDATSKTV 300
  301 TAEEGVPDGH MGLDVGPESS KIFAAAIQRA KTIVWNGPAG VFEFDKFATG TKSLMDEVVK 360
  361 ATAAGAITII GGGDTATAAK KYNTEDKVSH VSTGGGASLE LLEGKVLPGV DALSPAQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..417] PSI-BLAST 174.0 Structure of pig muscle PGK complexed with MgATP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoglycerate kinase activity
    		•  5.4060222740811 bayes_pls_golite062009
  • kinase activity
    		•  5.10875323814482 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.75644406547116 bayes_pls_golite062009
  • transferase activity
    		•  3.84971620558441 bayes_pls_golite062009
  • catalytic activity
    		•  2.30057758519011 bayes_pls_golite062009
  • phosphotransferase activity, carboxyl group as acceptor
    		•  2.28472985705972 bayes_pls_golite062009
  • binding
    		•  2.00400587462181 bayes_pls_golite062009
  • ATP binding
    		•  1.2270597395465 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.19223643201287 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.17740080861612 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.9898248694651 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.946046256290779 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.943434082819351 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.936146648259702 bayes_pls_golite062009
  • nucleotide binding
    		•  0.931721122227797 bayes_pls_golite062009
  • protein binding
    		•  0.206093694938779 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle