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Protein Overview: hacd-1

General Information:
Name(s) found: hacd-1 / CE12628 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00019978 locus:hacd-1 status:Confirmed UniProt:O44608 protein_id:CCD68882.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 299 amino acids

    Gene Ontology:
    Cellular Component: fatty acid beta-oxidation multienzyme complex [IEALink to PubMed article]
    Biological Process: fatty acid beta-oxidation [IEALink to PubMed article]
    fatty acid metabolic process [IEALink to PubMed article]
    Molecular Function: oxidoreductase activity [IEALink to PubMed article]
    3-hydroxyacyl-CoA dehydrogenase activity [IEALink to PubMed article]
    NAD or NADH binding [IEALink to PubMed article]
    3-hydroxybutyryl-CoA epimerase activity [IEALink to PubMed article]
    enoyl-CoA hydratase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQSGNENPK PLVAIFGAGM MGSGIAQVCL QAGYPVNLYG RSEKKLLEAR ETIKKNLIRV  60
   61 ASKKKTDVPM EPAALEEIAQ IQLDLLQIHT DIPSAAEDAA MAIEAVAENL DLKLDIFQTI 120
  121 QKTCPQNCML ITNTSSLKLS QMLPVIQNPA LFAGLHFFNP VPVMKLVEVV STDETSPETT 180
  181 NFLFNFCKEI KKLPVAAKDT PGFIVNRLLI PYLMDSIRML ERGDATKEDI DTAMRFGTSY 240
  241 PMGPIELCDY VGLDVLQSTL KIFRETIPGD ARFAPIPLMD KLVAEGKLGR KTKQGFYTY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..299] PSI-BLAST 75.39794 Short chain L-3-hydroxyacyl CoA dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity
    		•  3.09625241707629 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.65338499044318 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  1.61759001796638 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47309297191111 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  1.25489401408719 bayes_pls_golite062009
  • transporter activity
    		•  0.793769336118517 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.788034697021177 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.635891484075352 bayes_pls_golite062009
  • binding
    		•  0.553666136934364 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  0.530688665000667 bayes_pls_golite062009
  • phosphogluconate dehydrogenase (decarboxylating) activity
    		•  0.44449320501876 bayes_pls_golite062009
  • enoyl-CoA hydratase activity
    		•  0.439912268968251 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.300373102236296 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.239024094835991 bayes_pls_golite062009
  • signal transducer activity
    		•  0.201915860594054 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.201915860594054 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.165260811069909 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  0.0962368786590111 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.0257250793986203 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.27

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle