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Protein Overview: zen-4

General Information:
Name(s) found: zen-4 / CE12344 [WormBase]
Description(s) found:
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  • WBGene00006974 locus:zen-4 status:Confirmed UniProt:G5EG83 protein_id:CCD72297.1 [WormBase]
  • gi|71991845|ref|NP_001023309.1| Zygotic epidermal ENclosure defective family member (zen-4) [Caenorhabditis elegans] [NCBI NR]
  • gi|3493541|gb|AAC33437.1| kinesin-like protein ZEN-4a [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_741411.1| kinesin-like protein, Zygotic epidermal ENclosure defective ZEN-4 (87.7 kD) (zen-4) [Caenorhabditis elegans] [NCBI NR]
  • gi|1397341|gb|AAC24406.1| Zygotic epidermal enclosure defective protein 4, isoform a [Caenorhabditis elegans] [NCBI NR]
  • pir||T43033 kinesin-like protein ZEN-4a - Caenorhabditis elegans [NCBI NR]
  • [wormpep67.fasta]
  • CE12344 WBGene00006974 locus:zen-4 kinesin-like protein status:Confirmed TR:Q21493 protein_id:AAC24406.1 [wormpep150.fasta]
  • 12344 WBGene00006974 locus:zen-4 kinesin-like protein status:Confirmed TR:Q21493 protein_id:AAC24406.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • kinesin-like protein, Zygotic epidermal ENclosure defective ZEN-4 (87.7 kD) (zen-4) [Caenorhabditis elegans]gi|1397341|gb|AAC24406.1| Zygotic epidermal enclosure defective protein 4, isoform a [Caenorhabditis elegans]gi|3493541|gb|AAC33437.1| kinesin-li [nrdb_11152004_Chlamydomonas]
  • locus:zen-4 kinesin-like protein status:Confirmed TR:Q21493 protein_id:AAC24406.1 [wormpep115.fasta.reversed]
  • CE12344 locus:zen-4 kinesin-like protein status:Confirmed [wormpep80.hongbin]
  • CE12344 WBGene00006974 locus:zen-4 kinesin-like protein status:Confirmed UniProt:Q21493_CAEEL protein_id:AAC24406.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE12344 WBGene00006974 locus:zen-4 kinesin-like protein status:Confirmed UniProt:Q21493_CAEEL protein_id:AAC24406.1| [wormORF-contam.fasta]
  • Zygotic epidermal enclosure defective protein 4, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • kinesin-like protein ZEN-4a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Zygotic epidermal ENclosure defective family member (zen-4) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE12344 WBGene00006974 locus:zen-4 kinesin-like protein status:Confirmed UniProt:Q21493 protein_id:AAC24406.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE12344 WBGene00006974 locus:zen-4 kinesin-like protein status:Confirmed UniProt:G5EG83 protein_id:CCD72297.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE12344 WBGene00006974 locus:zen-4 status:Confirmed UniProt:G5EG83 protein_id:CCD72297.1 [wormpep246-ecoli-contam.fasta]
  • CE12344 WBGene00006974 locus:zen-4 status:Confirmed UniProt:G5EG83 protein_id:CCD72297.1 Kinesin-like protein [c_elegans-PRJNA13758-WS250-ecoli-contam.fasta]
  • Isoform of Q8MQ03, Kinesin-like protein OS=Caenorhabditis elegans GN=zen-4 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 775 amino acids

    Gene Ontology:
    Cellular Component: cleavage furrow [IDALink to PubMed article]
    microtubule associated complex [IEALink to PubMed article]
    Biological Process: embryonic cleavage [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    cytokinesis [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    microtubule-based movement [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article][ISSLink to PubMed article]
    microtubule motor activity [IEALink to PubMed article]
    plus-end-directed microtubule motor activity [ISSLink to PubMed article]
    microtubule binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRKRGITP SRDQVRRKKL SIEETDSIEV VCRLCPYTGS TPSLIAIDEG SIQTVLPPAQ  60
   61 FRRENAPQVE KVFRFGRVFS ENDGQATVFE RTSVDLILNL LKGQNSLLFT YGVTGSGKTY 120
  121 TMTGKPTETG TGLLPRTLDV IFNSINNRVE KCIFYPSALN TFEIRATLDA HLKRHQMAAD 180
  181 RLSTSREITD RYCEAIKLSG YNDDMVCSVF VTYVEIYNNY CYDLLEDARN GVLTKREIRH 240
  241 DRQQQMYVDG AKDVEVSSSE EALEVFCLGE ERRRVSSTLL NKDSSRSHSV FTIKLVMAPR 300
  301 AYETKSVYPT MDSSQIIVSQ LCLVDLAGSE RAKRTQNVGE RLAEANSINQ SLMTLRQCIE 360
  361 VLRRNQKSSS QNLEQVPYRQ SKLTHLFKNY LEGNGKIRMV ICVNPKPDDY DENMSALAFA 420
  421 EESQTIEVKK QVERMPSERI PHSFFTQWNS ELDGSVRMED DGSREIPCPP TFCLTDCNDK 480
  481 DTVDSMYKYA RKLSSLQNSS EEGPSSTLLT MIRQYMMEAD YQRVEIARLK DSLNDKDEEI 540
  541 KKLRGFCSRY KRENASMKER IASCEQGEQE NALVMEKLME QKMEDRKIIQ SQKKAMRNVR 600
  601 GIIDNPSPSV ASLRSRFDQE NVAHPTAPIQ TPPPPYQTPG RAPVFKKRLE ATTSTTVMSG 660
  661 SSSGGSGQQG YVNPKYQRRS KSASRLLDHQ PLHRVPTGTV LQSRTPANAI RTTKPEMHQL 720
  721 NKSGEYRLTH QEVDDEGNIS TNIVKGNVIP TVSGGTAVFF NDIERLTHES PSTRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..435] PSI-BLAST 75.221849 Kinesin
    2 View Details [436..775] PSI-BLAST 13.522879 Heavy meromyosin subfragment


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle