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Protein Overview: nhr-49

General Information:
Name(s) found: nhr-49 / CE12084 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00003639 locus:nhr-49 Nuclear hormone receptor family member nhr-49 status:Confirmed UniProt:O45666 protein_id:CAB05772.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 477 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    positive regulation of locomotion [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    steroid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLVDPLAEP CAVCGDKSTG THYGVISCNG CKGFFRRTVL RDQKFTCRFN KRCVIDKNFR  60
   61 CACRYCRFQK CVQVGMKREA IQFERDPVGS PTSGASLNGT PFKKDRSPGY ENGNSNGVGS 120
  121 NGMGQENMRT VPQSSSVIDA LMEMEARVNQ EMCNRYRRSQ IFANGSGGSN GNDTDIQQGS 180
  181 DSGASAFAPP NRPCTTEVDL NEISRTTLLL MVEWAKTINP FMDLSMEDKI ILLKNYAPQH 240
  241 LILMPAFRSP DTTRVCLFNN TYMTRDNNTD LNGFAAFKTS NITPRVLDEI VWPMRQLQMR 300
  301 EQEFVCLKAL AFLHPEAKGL SNSSQIMIRD ARNRVLKALY AFILDQMPDD APTRYGNILL 360
  361 LAPALKALTQ LLIENMTLTK FFGLAEVDSL LSEFILDDIN DHSTAPVSLQ QHLSSPTTLP 420
  421 TNGVSPLNPA GSVGSVSSVS GITPTGMLSA TLAAPLAIHP LQSQDSILNS EQNNHML

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..118] PSI-BLAST 24.154902 Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
    2 View Details [119..477] PSI-BLAST 48.0 No description for 2gl8A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle