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Protein Overview: puf-6

General Information:
Name(s) found: puf-6 / CE09451 [WormBase]
Description(s) found:
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  • WBGene00004242 locus:puf-6 Pumilio domain-containing protein 6 status:Confirmed UniProt:O01322 protein_id:CAB04133.1 [WormBase]
  • pir||T21080 hypothetical protein F18A11.1 - Caenorhabditis elegans [NCBI NR]
  • gi|3876074|emb|CAB04133.1| C. elegans protein F18A11.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17535395|ref|NP_496773.1| PUF (Pumilio/FBF) domain-containing family member (puf-6) [Caenorhabditis elegans] [NCBI NR]
  • Pumilio domain-containing protein 6 OS=Caenorhabditis elegans GN=puf-6 PE=2 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE09451 WBGene00004242 locus:puf-6 Pumilio-family RNA binding domains (aka PUM-HD, Pumilio homology domain) (6 domains) status:Partially_confirmed TR:O01322 protein_id:CAB04133.1 [wormpep150.fasta]
  • 09451 WBGene00004242 locus:puf-6 Pumilio-family RNA binding domains (aka PUM-HD, Pumilio homology domain) (6 domains) status:Partially_confirmed TR:O01322 protein_id:CAB04133.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • PUmilio and FBF family member (54.9 kD) (puf-6) [Caenorhabditis elegans]gi|3876074|emb|CAB04133.1| Hypothetical protein F18A11.1 [Caenorhabditis elegans]gi|7499342|pir||T21080 hypothetical protein F18A11.1 - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas]
  • locus:puf-6 Pumilio-family RNA binding domains (aka PUM-HD, Pumilio homology domain) (6 domains) status:Partially_confirmed TR:O01322 protein_id:CAB04133.1 [wormpep115.fasta.reversed]
  • CE09451 locus:puf-6 Pumilio-family RNA binding domains (aka PUM-HD, Pumilio homology domain) (6 domains) status:Partially_confirmed TR:O01322 protein_id:CAB04133.1 [wormpep80.hongbin]
  • CE09451 WBGene00004242 locus:puf-6 Pumilio-family RNA binding domains (aka PUM-HD, Pumilio homology domain) (6 domains) status:Confirmed UniProt:O01322_CAEEL protein_id:CAB04133.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE09451 WBGene00004242 locus:puf-6 Pumilio-family RNA binding domains (aka PUM-HD, Pumilio homology domain) (6 domains) status:Confirmed UniProt:O01322_CAEEL protein_id:CAB04133.1| [wormORF-contam.fasta]
  • Hypothetical protein F18A11.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • PUF (Pumilio/FBF) domain-containing family member (puf-6) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE09451 WBGene00004242 locus:puf-6 Pumilio-family RNA binding domains (aka PUM-HD, Pumilio homology domain) (6 domains) status:Confirmed TR:O01322 protein_id:CAB04133.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • CE09451 WBGene00004242 locus:puf-6 Pumilio-family RNA binding domains (aka PUM-HD, Pumilio homology domain) (6 domains) status:Confirmed UniProt:O01322 protein_id:CAB04133.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE09451 WBGene00004242 locus:puf-6 status:Confirmed UniProt:O01322 protein_id:CAB04133.1 Pumilio domain-containing protein 6 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 485 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISSLink to PubMed article]
    Biological Process: germ cell development [IMPLink to PubMed article]
    negative regulation of cell proliferation [IMPLink to PubMed article]
    mRNA catabolic process [ISSLink to PubMed article]
    Molecular Function: RNA binding [IEALink to PubMed article]
    mRNA 3'-UTR binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPNRRSTDS YNMLGASFDF DPDFSLLSNK THKNKNPKPP VKLLPYRHGS NTTSSDLDNY  60
   61 IFNSGSGSSD DETPPPAAPI FISLEEVLLN GLLIDFAIDP SGVKFLEANY PLDSEDQIRK 120
  121 AVFEKLTEST TLFVGLCHSR NGNFIVQKLV ELATPAEQRE LLRQMIDGGL LVMCKDKFAC 180
  181 RVVQLALQKF DHSNVFQLIQ ELSTFDLAAM CTDQISIHVI QRVVKQLPVD MWTFFVHFLS 240
  241 SGDSLMAVCQ DKYGCRLVQQ VIDRLAENPK LPCFKFRIQL LHSLMTCIVR NCYRLSSNEF 300
  301 ANYVIQYVIK SSGIMEMYRD TIIDKCLLRN LLSMSQDKYA SHVIEGAFLF APPALLHEMM 360
  361 EEIFSGYVKD VELNRDALDI LLFHQYGNYV VQQMISICTA ALIGKEERQL PPAILLLYSG 420
  421 WYEKMKQRVL QHASRLERFS SGKKIIDSVM RHGVPTAAAI NAQAAPSLME LTAQFDAMFP 480
  481 SFLAR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..485] PSI-BLAST 98.221849 Pumilio 1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.72717267135753 bayes_pls_golite062009
  • protein binding
    		•  1.01840651819417 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle