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Protein Overview: mec-10

General Information:
Name(s) found: mec-10 / CE09444 [WormBase]
Description(s) found:
Found 25 descriptions.
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  • WBGene00003174 locus:mec-10 Degenerin mec-10 status:Confirmed UniProt:P34886 protein_id:CCD69038.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 724 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: mechanosensory behavior [IMPLink to PubMed article]
    sodium ion transport [IEALink to PubMed article]
    ion transport [IEALink to PubMed article]
    response to mechanical stimulus [IMPLink to PubMed article]
    Molecular Function: ion channel activity [IEALink to PubMed article]
    sodium channel activity [IEALink to PubMed article]
    amiloride-sensitive sodium channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRNPRMSKF QPNPRSRSRF QDETDLRSLR SFKTDFSNYL ASDTNFLNVA EIMTSYAYGE  60
   61 SNNAHEKEIQ CDLLTENGGI EIDPTRLSYR ERIRWHLQQF CYKTSSHGIP MLGQAPNSLY 120
  121 RAAWVFLLLI CAIQFINQAV AVIQKYQKMD KITDIQLKFD TAPFPAITLC NLNPYKDSVI 180
  181 RSHDSISKIL GVFKSVMKKA GDSSSEALEE EEETEYDMNG ITIQAKRKKR GAGEKGTFEP 240
  241 ANSACECDEE DGSNECEERS TEKPSGDNDM CICAFDRQTN DAWPCHRKEQ WTNTTCQTCD 300
  301 EHYLCSKKAK KGTKRSELKK EPCICESKGL FCIKHEHAAM VLNLWEYFGD SEDFSEISTE 360
  361 EREALGFGNM TDEVAIVTKA KENIIFAMSA LSEEQRILMS QAKHNLIHKC SFNGKPCDID 420
  421 QDFELVADPT FGNCFVFNHD REIFKSSVRA GPQYGLRVML FVNASDYLPT SEAVGIRLTI 480
  481 HDKDDFPFPD TFGYSAPTGY ISSFGMRMKK MSRLPAPYGD CVEDGATSNY IYKGYAYSTE 540
  541 GCYRTCFQEL IIDRCGCSDP RFPSIGGVQP CQVFNKNHRE CLEKHTHQIG EIHGSFKCRC 600
  601 QQPCNQTIYT TSYSEAIWPS QALNISLGQC EKEAEECNEE YKENAAMLEV FYEALNFEVL 660
  661 SESEAYGIVK MMADFGGHLG LWSGVSVMTC CEFVCLAFEL IYMAIAHHIN QQRIRRRENA 720
  721 ANEY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..85] deduced N/A No confident structure predictions are available.
    2 View Details [86..268] FFAS03 3.8 No description for 2qtsA was found.
    3 View Details [269..724] PSI-BLAST 82.69897 No description for 2qtsA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.24

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle