Protein Overview: pyc-1

General Information:
Name(s) found:	pyc-1 / CE09072 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00004258 locus:pyc-1 Pyruvate carboxylase 1 status:Confirmed UniProt:O17732 protein_id:CAB02872.1 [WormBase] pir\|\|T20346 pyruvate carboxylase (EC 6.4.1.1) D2023.2 [similarity] - Caenorhabditis elegans [NCBI NR] gi\|74957739\|sp\|O17732.1\|PYC1_CAEEL RecName: Full=Pyruvate carboxylase 1; AltName: Full=Pyruvic carboxylase 1; Short=PCB 1 [NCBI NR] gi\|7331216\|gb\|AAF60326.1\|AF237467_1 pyruvate carboxylase [Caenorhabditis elegans] [NCBI NR] gi\|3875406\|emb\|CAB02872.1\| C. elegans protein D2023.2, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|17562816\|ref\|NP_505977.1\| PYruvate Carboxylase family member (pyc-1) [Caenorhabditis elegans] [NCBI NR] Pyruvate carboxylase 1 OS=Caenorhabditis elegans GN=pyc-1 PE=1 SV=1 [Swiss-Prot] [wormpep67.fasta] CE09072 WBGene00004258 locus:pyc-1 pyruvate carboxylase status:Confirmed TR:O17732 protein_id:CAB02872.1 [wormpep150.fasta] 09072 WBGene00004258 locus:pyc-1 pyruvate carboxylase status:Confirmed TR:O17732 protein_id:CAB02872.1 [wormpep130-phg-ecoli-orf-rand.fasta] pyruvate carboxylase, Biotin-requiring, cadmium-responsive gene (129.3 kD) (pyc-1) [Caenorhabditis elegans]gi\|3875406\|emb\|CAB02872.1\| Hypothetical protein D2023.2 [Caenorhabditis elegans]gi\|7331216\|gb\|AAF60326.1\| pyruvate carboxylase [Caenorhabditis ele [nrdb_11152004_Chlamydomonas] locus:pyc-1 pyruvate carboxylase status:Confirmed TR:O17732 protein_id:CAB02872.1 [wormpep115.fasta.reversed] CE09072 locus:pyc-1 pyruvate carboxylase status:Confirmed TR:O17732 protein_id:CAB02872.1 [wormpep80.hongbin] CE09072 WBGene00004258 locus:pyc-1 pyruvate carboxylase status:Confirmed UniProt:PYC1_CAEEL protein_id:CAB02872.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE09072 WBGene00004258 locus:pyc-1 pyruvate carboxylase status:Confirmed UniProt:PYC1_CAEEL protein_id:CAB02872.1\| [wormORF-contam.fasta] Hypothetical protein D2023.2 [Caenorhabditis elegans] [nr-271106-contam.fasta] pyruvate carboxylase [Caenorhabditis elegans] [nr-271106-contam.fasta] Pyruvate carboxylase 1 (Pyruvic carboxylase 1) (PCB 1) [nr-271106-contam.fasta] PYruvate Carboxylase family member (pyc-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE09072 WBGene00004258 locus:pyc-1 pyruvate carboxylase status:Confirmed SW:O17732 protein_id:CAB02872.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta] CE09072 WBGene00004258 locus:pyc-1 pyruvate carboxylase status:Confirmed UniProt:O17732 protein_id:CAB02872.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE09072 WBGene00004258 locus:pyc-1 status:Confirmed UniProt:O17732 protein_id:CAB02872.1 Pyruvate carboxylase 1 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	1175 amino acids
Gene Ontology:
Cellular Component:	phosphoribosylaminoimidazole carboxylase complex [IEA] cytoplasm [IEA]
Biological Process:	sodium ion transport [IEA] gluconeogenesis [IEA] metabolic process [IEA] peptidoglycan biosynthetic process [IEA] protein modification process [IEA] 'de novo' IMP biosynthetic process [IEA] purine base biosynthetic process [IEA] carboxylic acid metabolic process [IEA]
Molecular Function:	oxaloacetate decarboxylase activity [IEA] ATP binding [IEA] D-alanine-D-alanine ligase activity [IEA] phosphoribosylaminoimidazole carboxylase activity [IEA] catalytic activity [IEA] pyruvate carboxylase activity [IEA] transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [IEA] ligase activity [IEA] hydroxymethyl-, formyl- and related transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFSRIPPIF ANVVRQTHYR NYANGVIKPR EFNKVMVANR GEIAIRVFRA LTELNKTSVA  60
   61 IYAEQDKNSM HRLKADEAYL VGKGLPPVAA YLTIDQIIET ALKHNIDAIH PGYGFLSERS 120
  121 DFAAACQNAG IVFIGPSPDV MARMGDKVAA RQAAIEAGVQ VVPGTPGPIT TADEAVEFAK 180
  181 QYGTPIILKA AYGGGGRGIR RVDKLEEVEE AFRRSYSEAQ AAFGDGSLFV EKFVERPRHI 240
  241 EVQLLGDHHG NIVHLYERDC SVQRRHQKVV EIAPAPALPE GVREKILADA LRLARHVGYQ 300
  301 NAGTVEFLVD QKGNYYFIEV NARLQVEHTV TEEITGVDLV QAQIRIAEGK SLDDLKLSQE 360
  361 TIQTTGSAIQ CRVTTEDPAK GFQPDSGRIE VFRSGEGMGI RLDSASAFAG SVISPHYDSL 420
  421 MVKVIASARN HPNAAAKMIR ALKKFRIRGV KTNIPFLLNV LRQPSFLDAS VDTYFIDEHP 480
  481 ELFQFKPSQN RAQKLLNYLG EVKVNGPTTP LATDLKPAVV SPPIPYIPAG AKPPTGLRDV 540
  541 LVQRGPTEFA KEVRSRPGCM ITDTTFRDAH QSLLATRVRT YDMAAISPFV AQSFNGLFSL 600
  601 ENWGGATFDV SMRFLHECPW ERLQTLRKLI PNIPFQCLLR GANAMGYSNY PDNVIYKFCE 660
  661 LAVKNGMDVF RVFDSLNYLP NLLVGMEAVG KAGGVVEAAI AYTGDVTDKS RDKYDLKYYL 720
  721 NLADQLVKAQ AHILSIKDMA GVLKPEAAKL LIGALRDKFP DIPIHVHTHD TSGAGVAAML 780
  781 ECAKAGADVV DAAVDSMSGM TSQPSMGAIV ASLQGTKHDT GLSLDDISKY SAYWESTRQL 840
  841 YAPFECATTM KSGNADVYKH EIPGGQYTNL QFQAFSLGLG PQFDEVKRMY REANLVLGDI 900
  901 IKVTPSSKIV GDLAQFMVQN NLTRETLVDR ADDLSFPKSV VDFMQGNVGQ PPYGFPEPLR 960
  961 TKVLRGKPKV DGRPGENAKP VDLDAVKVEL EEKHGRTLSE EDVMSYSMFP TVFDEFETFR1020
 1021 QQYGPVDKLP TRLFLTGLEI AEEVDVEIES GKTLAIQLLA EGKLNKRGER EVFFDLNGQM1080
 1081 RSIFVVDKEA SKEIVTRPRA LPGVRGHIGA PMPGDVLELK IKEGDKVTKK QPLFVLSAMK1140
 1141 MEMVIDSPIA GTVKAIHAPQ GTKCSAGDLV VEVEP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-1	hcp1 IP from december2004	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: pyc-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: