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Protein Overview: nhx-3

General Information:
Name(s) found: nhx-3 / CE08985 [WormBase]
Description(s) found:
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  • WBGene00003731 locus:nhx-3 Probable Na(+)\/H(+) antiporter nhx-3 status:Confirmed UniProt:O16452 protein_id:CCD62993.1 [WormBase]
  • pir||T31869 hypothetical protein C54F6.13 - Caenorhabditis elegans [NCBI NR]
  • gi|71987537|ref|NP_001023736.1| Na/H eXchanger family member (nhx-3) [Caenorhabditis elegans] [NCBI NR]
  • gi|39752856|gb|AAR30208.1| Na/h exchanger protein 3, isoform b [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • Na/h exchanger protein 3, isoform b [Caenorhabditis elegans]gi|7497933|pir||T31869 hypothetical protein C54F6.13 - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas]
  • CE08985 WBGene00003731 locus:nhx-3 status:Confirmed SW:O16452 protein_id:AAR30208.1 [wormpep150.fasta]
  • 08985 WBGene00003731 locus:nhx-3 status:Partially_confirmed TR:Q71VC7 protein_id:AAR30208.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • CE08985 WBGene00003731 locus:nhx-3 status:Partially_confirmed TR:Q71VC7 protein_id:AAR30208.1 [wormpep132.fasta]
  • 08985 WBGene00003731 locus:nhx-3 status:Confirmed SW:O16452 protein_id:AAR30208.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE08985 WBGene00003731 locus:nhx-3 status:Confirmed TR:Q71VC7 protein_id:AAR30208.1 [WormBase_C-elegans_na_01-20-2005_combined_reversed.fasta]
  • CE08985 locus:nhx-3 status:Partially_confirmed [wormpep80.hongbin]
  • CE08985 WBGene00003731 locus:nhx-3 status:Confirmed UniProt:O16452 protein_id:AAR30208.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE08985 WBGene00003731 locus:nhx-3 status:Confirmed UniProt:O16452 protein_id:AAR30208.1| [wormORF-contam.fasta]
  • Na/H eXchanger family member (nhx-3) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Na/h exchanger protein 3, isoform b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE08985 WBGene00003731 locus:nhx-3 status:Confirmed UniProt:O16452 protein_id:CCD62993.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE08985 WBGene00003731 locus:nhx-3 status:Confirmed UniProt:O16452 protein_id:CCD62993.1 Probable Na(+)\/H(+) antiporter nhx-3 [wormpep246-ecoli-contam.fasta]
  • Isoform of O16452, Isoform b of Probable Na(+)/H(+) antiporter nhx-3 OS=Caenorhabditis elegans GN=nhx-3 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 651 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: sodium ion transport [IEALink to PubMed article]
    regulation of pH [IEALink to PubMed article]
    Molecular Function: solute:hydrogen antiporter activity [IEALink to PubMed article]
    sodium:hydrogen antiporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVRDYGLAE LFHWNWDHIH KVYVITTWLL VASLAKILFN LMKPLSKWLP DSSLLIIVGL  60
   61 GLGYFLNQTT LSGVHLDSHA FFLYLLPPII FDAGYFMPNR ALFKNFDSVL VFSVLGTLWN 120
  121 TFAIGGSLLI MSKYQLFTMP FTTFEILVFS ALISAVDPVA VIAIFEEIHV NEFLFINVFG 180
  181 EALFNDGVTV VLYQMFKSFA LIGSENLSPW DYATGGLSFF VVALGGAAIG IIFAIATSLA 240
  241 TKYTQGIKIL APVFIFLLPY MAYLTAEMVS LSSIIAIAVC GMLMKQYIKG NITEAATNSV 300
  301 KYFTKMLAQC SETVIFMFLG LSTLTSEHHV DFIFIGATLV FCLIYRAIGI IVQCFILNKF 360
  361 RAKKFEVVDQ FILSYGGLRG AIAYGLVVSI PASIQAKPMF ITTTICVIYF TVFLQGITIR 420
  421 PLVNCLNVKK KEHREATMVE SVYNKYLDYM MSGVEDIAGQ RGHYSFIENF ERFNAKVIKP 480
  481 VLMRHEKRQS FDATSIIRAY EKITLEDAIK LTKVKSTLQN KRLEKVKSEV RVAPEQTTVT 540
  541 PKDVQLARFM QSGENIDQLY TLFSDLLDKK LNELKVQADK VDKANDDDIQ DDYMAEMGSH 600
  601 SNLGFMHHSA DQLDSDSVFQ RRGRRLSTGD LKGHCGTSRK PKHSMFELRH V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..137] MSA 6.050994 View MSA. No confident structure predictions are available.
    2 View Details [138..289] MSA 2.050996 View MSA. No confident structure predictions are available.
    3 View Details [290..416] MSA 4.032992 View MSA. No confident structure predictions are available.
    4 View Details [417..514] FFAS03 1.07 A DESIGNED FOUR HELIX BUNDLE PROTEIN.
    5 View Details [515..651] PSI-BLAST 8.154902 No description for 2i1jA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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