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Protein Overview: bir-2

General Information:
Name(s) found: bir-2 / CE08882 [WormBase]
Description(s) found:
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  • WBGene00000250 locus:bir-2 status:Confirmed UniProt:G5ECJ5 protein_id:CAB01130.1 [WormBase]
  • pir||T37474 apoptosis inhibitor homolog C50B8.2 - Caenorhabditis elegans [NCBI NR]
  • gi|4097917|gb|AAD00182.1| inhibitor of apoptosis homolog [Caenorhabditis elegans] [NCBI NR]
  • gi|3875145|emb|CAB01130.1| C. elegans protein C50B8.2, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17557418|ref|NP_506362.1| BIR (baculovirus inhibitory repeat) family member (bir-2) [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE08882 WBGene00000250 locus:bir-2 Inhibitor of Apoptosis domain. status:Confirmed TR:Q18727 protein_id:CAB01130.1 [wormpep150.fasta]
  • 08882 WBGene00000250 locus:bir-2 Inhibitor of Apoptosis domain. status:Confirmed TR:Q18727 protein_id:CAB01130.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • baculovirus Inhibitory Repeat family member (35.4 kD) (bir-2) [Caenorhabditis elegans]gi|3875145|emb|CAB01130.1| Hypothetical protein C50B8.2 [Caenorhabditis elegans]gi|4097917|gb|AAD00182.1| inhibitor of apoptosis homolog [Caenorhabditis elegans]gi|74 [nrdb_11152004_Chlamydomonas]
  • locus:bir-2 Inhibitor of Apoptosis domain. status:Confirmed TR:Q18727 protein_id:CAB01130.1 [wormpep115.fasta.reversed]
  • CE08882 locus:bir-2 Inhibitor of Apoptosis domain. status:Confirmed TR:Q18727 protein_id:CAB01130.1 [wormpep80.hongbin]
  • CE08882 WBGene00000250 locus:bir-2 Inhibitor of Apoptosis domain. status:Confirmed UniProt:Q18727_CAEEL protein_id:CAB01130.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE08882 WBGene00000250 locus:bir-2 Inhibitor of Apoptosis domain. status:Confirmed UniProt:Q18727_CAEEL protein_id:CAB01130.1| [wormORF-contam.fasta]
  • BIR (baculovirus inhibitory repeat) family member (bir-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • inhibitor of apoptosis homolog [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein C50B8.2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE08882 WBGene00000250 locus:bir-2 Inhibitor of Apoptosis domain. status:Confirmed UniProt:Q18727 protein_id:CAB01130.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE08882 WBGene00000250 locus:bir-2 Inhibitor of Apoptosis domain. status:Confirmed UniProt:G5ECJ5 protein_id:CAB01130.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE08882 WBGene00000250 locus:bir-2 status:Confirmed UniProt:G5ECJ5 protein_id:CAB01130.1 [wormpep246-ecoli-contam.fasta]
  • BIR (Baculovirus inhibitory repeat) family OS=Caenorhabditis elegans GN=bir-2 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 308 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEALink to PubMed article]
    Biological Process: anti-apoptosis [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    determination of adult lifespan [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPYTFENSEA LLKNLKDAAP YISAAERFAS FKGFVYDKRI NIACTSEKLA RAGFYSTASP  60
   61 EFPASAKCPF CMLEINFEQC DDPWEKHKSG SPHCEFVMIG EIEESELSFR IISNLAIRHA 120
  121 TVRLYEELLG IVATLENGDI ANENPITRAD ATRKLISFRS SSKLLTFDHR LATFQNFIFD 180
  181 KKRNVKCTSK KLAKAGWFSI ANKKDKTSAK CPFCLVELDF DESDDPWEEH QKFSASCDFI 240
  241 KLGKLDEKKW TENEALMLGA RITIMQKYEK GSWLIDELEK ENRIDEIIKI RKIMIKPNHV 300
  301 LKRRRCSI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..131] PSI-BLAST 27.154902 Anti-apoptotic protein survivin
    2 View Details [132..308] PSI-BLAST 27.221849 BIR2 domain of DIAP1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  1.08201190414623 bayes_pls_golite062009
  • binding
    		•  1.04832973985677 bayes_pls_golite062009
    2
    Term Confidence Notes
  • protein binding
    		•  1.08201190414623 bayes_pls_golite062009
  • binding
    		•  1.04832973985677 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle