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Protein Overview: asic-2

General Information:
Name(s) found: asic-2 / CE06524 [WormBase]
Description(s) found:
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  • WBGene00012137 locus:asic-2 Degenerin-like protein asic-2 status:Partially_confirmed UniProt:Q22851 protein_id:CAA96693.1 [WormBase]
  • pir||T25429 hypothetical protein T28F4.2 - Caenorhabditis elegans [NCBI NR]
  • gi|3880345|emb|CAA96693.1| C. elegans protein T28F4.2, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|2500844|sp|Q22851.1|ASIC2_CAEEL RecName: Full=Degenerin-like protein asic-2; AltName: Full=Acid-sensing/amiloride-sensitive ion channel protein 2 [NCBI NR]
  • gi|17509335|ref|NP_492099.1| Acid-sensing/Amiloride-Sensitive Ion Channel family member (asic-2) [Caenorhabditis elegans] [NCBI NR]
  • (Q22851) Degenerin-like protein T28F4.2 in chromosome I [Swiss-Prot]
  • Degenerin-like protein asic-2 OS=Caenorhabditis elegans GN=asic-2 PE=3 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE06524 WBGene00012137 locus:asic-2 mechanosensory protein like status:Partially_confirmed SW:Q22851 protein_id:CAA96693.1 [wormpep150.fasta]
  • 06524 WBGene00012137 mechanosensory protein like status:Partially_confirmed SW:Q22851 protein_id:CAA96693.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • degenerin mec-4 family member (1I59) [Caenorhabditis elegans]gi|3880345|emb|CAA96693.1| Hypothetical protein T28F4.2 [Caenorhabditis elegans]gi|7508696|pir||T25429 hypothetical protein T28F4.2 - Caenorhabditis elegansgi|2500844|sp|Q22851|DEGW_CAEEL Deg [nrdb_11152004_Chlamydomonas]
  • CE06524 WBGene00012137 mechanosensory protein like status:Partially_confirmed SW:Q22851 protein_id:CAA96693.1 [wormpep132.fasta]
  • 06524 WBGene00012137 locus:asic-2 mechanosensory protein like status:Partially_confirmed SW:Q22851 protein_id:CAA96693.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • mechanosensory protein like status:Partially_confirmed SW:Q22851 protein_id:CAA96693.1 [wormpep115.fasta.reversed]
  • CE06524 mechanosensory protein like status:Predicted SW:Q22851 protein_id:CAA96693.1 [wormpep80.hongbin]
  • CE06524 WBGene00012137 locus:asic-2 mechanosensory protein like status:Partially_confirmed UniProt:Q22851 protein_id:CAA96693.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE06524 WBGene00012137 locus:asic-2 mechanosensory protein like status:Partially_confirmed UniProt:Q22851 protein_id:CAA96693.1| [wormORF-contam.fasta]
  • Hypothetical protein T28F4.2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Degenerin-like protein asic-2 (Acid-sensing/amiloride-sensitive ion channel protein 2) [nr-271106-contam.fasta]
  • Acid-sensing/Amiloride-Sensitive Ion Channel family member (asic-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE06524 WBGene00012137 locus:asic-2 status:Partially_confirmed UniProt:Q22851 protein_id:CAA96693.1 Degenerin-like protein asic-2 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 545 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: sodium ion transport [IEALink to PubMed article]
    ion transport [IEALink to PubMed article]
    Molecular Function: ion channel activity [IEALink to PubMed article]
    sodium channel activity [IEALink to PubMed article]
    amiloride-sensitive sodium channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGGGFVQIF KDFSNWSTVA VVPHVANANN KISRIFWIAI FLFVLGMFAY ELYILIAKFF  60
   61 SYPATVNTEI LFEKQIFPVV TVCNMNPYKY SVVKSNSAFS SVNTLMTTYS DATVGTFSTD 120
  121 KWGLYADNDE TYDLDSRAAD ALVLEANLIS DTAKVPALYT YADLIQDCSF AGIPCSESDF 180
  181 TKFIDPVYGA CYSFNEDASL NYSVSREGIQ FGLKLMLTVT QTKTNGNTDS LPTTKLAGAR 240
  241 IGVNSRGSSP GLDSNGIDAG VGYESAVSVS LTQNVRAKKP YGTCVDREPD SSDYYKDFIY 300
  301 TLETCFNGCK QRDTIAKCQC ANPRLALGST DTACQPIKAD LDCLQTLKGN QTSSTPNIDL 360
  361 LVECNCNPPC DESTYTPTVS LAQFPSTSYY VATSSTAGVG SCSSTNSKFS SKSDCQKWYN 420
  421 NNGMIIQVFL ETLSYELYTE TAGYTVSNVI NDLGGQAGLW LGLSVISVVE MTGLMLVMGA 480
  481 FCVTGGAIKM APDDDEIEND HRIKDVEDVK KEIDHLEKKH GEMESGSDGE VDDIENKGDE 540
  541 EKKKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..545] PSI-BLAST 98.221849 No description for 2qtsA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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