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Protein Overview: imp-2

General Information:
Name(s) found: imp-2 / CE06364 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00011481 locus:imp-2 Intramembrane protease 2 status:Confirmed UniProt:P49049 protein_id:CAA92975.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 468 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: negative regulation of multicellular organism growth [IMPLink to PubMed article]
    molting cycle, protein-based cuticle [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    Molecular Function: aspartic-type endopeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEAATEIPP TASNVTVFTF EEQATSSLAL YGMSILCIII GSIRSAQYIR TNIDKKRLIE  60
   61 GSITMREARK FPISASLVLF GLYLFFKPAA ERFLWVARVF QILRVPEEYV QKINSTIISY 120
  121 TANTTTTGPS EPFLLRLASR IPQERVPEAI QNAATYAYTN LPTIQKAECM QLLTFLICFE 180
  181 GVNAFASLLK PFVTAFLKKM PLVPSFLRFN APYLFSLKKG NKEMEEGDIE DAKKKETEYL 240
  241 FKIDFDRYDI IALLMCSPIL ISHLLKRHWI TNNIIGVSFS ILGIERLHLA SFKAGSLLLV 300
  301 GLFFYDIFWV FGTDVMTSVA KGIDAPILLQ FPQDIYRNGI MEASKHSMLG LGDIVIPGIF 360
  361 IALLRRFDYR VVQTTAESKA PQGSLKGRYY FVVTVVAYMA GLFITMAVMH HFKAAQPALL 420
  421 YLVPCCLFVP LLLAVIRGEL SALWNYDESR HVDNEENRKK VDSGKKNN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..121] MSA 2.054986 View MSA. No confident structure predictions are available.
    2 View Details [122..346] MSA 4.108994 View MSA. No confident structure predictions are available.
    3 View Details [347..468] MSA 1.107992 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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