Protein Overview: apr-1

General Information:
Name(s) found:	apr-1 / CE06102 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00000156 locus:apr-1 Adenomatous polyposis coli protein-related protein 1 status:Confirmed UniProt:Q21227 protein_id:CAB00045.1 [WormBase] pir\|\|T23327 adenomatous polyposis coli protein 1 - Caenorhabditis elegans [NCBI NR] gi\|3878267\|emb\|CAB00045.1\| C. elegans protein K04G2.8a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|25145557\|ref\|NP_492217.2\| APC Related family member (apr-1) [Caenorhabditis elegans] [NCBI NR] gi\|2338718\|gb\|AAC47747.1\| APR-1 [Caenorhabditis elegans] [NCBI NR] [wormpep67.fasta] CE06102 WBGene00000156 locus:apr-1 status:Confirmed TR:Q21227 protein_id:CAB00045.1 [wormpep150.fasta] 06102 WBGene00000156 locus:apr-1 status:Confirmed TR:Q21227 protein_id:CAB00045.1 [wormpep130-phg-ecoli-orf-rand.fasta] adenomatosis Polyposis Coli Related (131.7 kD) (apr-1) [Caenorhabditis elegans]gi\|3878267\|emb\|CAB00045.1\| Hypothetical protein K04G2.8a [Caenorhabditis elegans]gi\|2338718\|gb\|AAC47747.1\| APR-1 [Caenorhabditis elegans]gi\|7494524\|pir\|\|T23327 adenomatous p [nrdb_11152004_Chlamydomonas] locus:apr-1 status:Confirmed TR:Q21227 protein_id:CAB00045.1 [wormpep115.fasta.reversed] CE06102 locus:apr-1 status:Confirmed protein_id:CAB00045.1 [wormpep80.hongbin] CE06102 WBGene00000156 locus:apr-1 status:Confirmed UniProt:Q21227_CAEEL protein_id:CAB00045.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE06102 WBGene00000156 locus:apr-1 status:Confirmed UniProt:Q21227_CAEEL protein_id:CAB00045.1\| [wormORF-contam.fasta] Hypothetical protein K04G2.8a [Caenorhabditis elegans] [nr-271106-contam.fasta] APC Related family member (apr-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] APR-1 [Caenorhabditis elegans] [nr-271106-contam.fasta] CE06102 WBGene00000156 locus:apr-1 status:Confirmed UniProt:Q21227 protein_id:CAB00045.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE06102 WBGene00000156 locus:apr-1 status:Confirmed UniProt:Q21227 protein_id:CAB00045.1 Adenomatous polyposis coli protein-related protein 1 [wormpep246-ecoli-contam.fasta] Isoform of Q21227, Isoform a of Adenomatous polyposis coli protein-related protein 1 OS=Caenorhabditis elegans GN=apr-1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	1186 amino acids
Gene Ontology:
Cellular Component:	adherens junction [IDA] cytoplasm [IDA]
Biological Process:	negative regulation of vulval development [IGI][IMP] embryonic cleavage [IMP] spindle organization [IMP] vulval development [IGI][IMP] embryonic development ending in birth or egg hatching [IMP ] post-embryonic body morphogenesis [IMP ] positive regulation of transcription from RNA polymerase II promoter [IMP] reproduction [IMP] growth [IMP ] locomotory behavior [IMP ] nematode larval development [IMP ] embryonic morphogenesis [IMP] endodermal cell fate specification [IGI][IMP] negative regulation of Wnt receptor signaling pathway [IGI] positive regulation of Wnt receptor signaling pathway [IGI] regulation of cell migration [IMP] regulation of embryonic cell shape [IMP] cell fate specification [IGI][IMP]
Molecular Function:	beta-catenin binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSSSDENE TTIHRTGSNT GGSGIYSQPR AGSSKRTSNV RHDVSDVDDE EEHYARFRED  60
   61 TAIEVDDAIT VLLSSLHFEH KRDIVPTDED DNKLRELHEK IFALITSESD VNRKRRLKKA 120
  121 LPASNCVREQ VYYLRRKPST PPASYYHRLN AALHTIVKES FGEEYRKVAT VLGLVEALAE 180
  181 VLILEVHTFG INETNPGEHR NIRKLIANAL TNLTYGQIHS KRRLCSYDGF IRCVVRIVIE 240
  241 SPNITQVYAG LIRNLSWNAD SGMSEALQPT VHALSIAAVH AHTHRFDVTA TLSALWNLAG 300
  301 HSVENKRTIC DTPNCLKVLA SLLSPDARFT SLVDSATGIL KYVSQYLANT STHLELRSLL 360
  361 ITRMLTLLKS ASFTCVTNTL GAIANLIVKD PHMQQMIRQD MAAVQQLNVL RNSNRDDIRT 420
  421 AVKSVLNTLN QPCSHRYGDM SHSVGGGATG MQMLSEPQLQ MQTSHHAYHG TASPRLLSLR 480
  481 ATRASPGKYI QPQAQQQLIQ TPQVDQRSSS LPRHFAVQRN GFVMAQSYNQ QMDQHQQQQM 540
  541 IYQLQQQQQI MTEDQAQMEH HQQIMYLQQQ QQQFHQIQQQ QQMQKAQEAD PVPPTDDDLD 600
  601 IPTSTVMGTR SNSERSLGSM NPGSVMTNWN SSLDTAANSS RALSPVSYND IPASPTMCAQ 660
  661 VFNLPKSTES EHHQLTSQQQ NTTHYSSGSA NTMTRSDGAT TVPMDNIITP TYAILNPILV 720
  721 HEQTPNGTVP RKTSEELDSP DDVLPGPSLE EEEGDYAIIG GAAQKTDDEL LTRSIQSEMP 780
  781 TSSSTPKMKV SPRLNGFFSP TQKTTSSPAW SHPDTSPIPK SSSHRTQPNR RQDASDADRL 840
  841 LMESIMSEMP KSRIISPRLA GTQQYLEPEP ERRSHSKNEE ADRRDAFTAS HEPSDHNGID 900
  901 VARGSDWSPQ QQLHRMESLE SQASSEDSFG LTAEEPNSST SGAAANTMRF DDEIDASLPM 960
  961 DCVDDDDYDY TYDHFEDYED EEDPDATQFD DGVDAQLTID CSMISSGSGS SQRNETTTTS1020
 1021 RDSKALATST PKGSASSLPG VRQATRVSTN GKSRLPVPKT NGSLVDKNPK PIIASRRPRL1080
 1081 PPKPTLLKDK HYPEEDSIEN QTRDDTIYVN APVVEAEQER IYMNALKQQK NIEQSPSIGN1140
 1141 GSPIAKSAIV TPYNYQKPPF TGRNNGEMSN EKSVTPNPKQ MLVTIV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Protein Overview: apr-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: