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Protein Overview: daf-21

General Information:
Name(s) found: daf-21 / CE05441 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00000915 locus:daf-21 Heat shock protein 90 status:Confirmed UniProt:Q18688 protein_id:CAA99793.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 702 amino acids

    Gene Ontology:
    Cellular Component: perinuclear region of cytoplasm [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: dauer larval development [IGILink to PubMed article][IMPLink to PubMed article]
    determination of adult lifespan [IGILink to PubMed article]
    protein folding [IEALink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    unfolded protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSENAETFAF QAEIAQLMSL IINTFYSNKE IYLRELISNA SDALDKIRYQ ALTEPSELDT  60
   61 GKELFIKITP NKEEKTLTIM DTGIGMTKAD LVNNLGTIAK SGTKAFMEAL QAGADISMIG 120
  121 QFGVGFYSAF LVADKVVVTS KNNDDDSYQW ESSAGGSFVV RPFNDPEVTR GTKIVMHIKE 180
  181 DQIDFLEERK IKEIVKKHSQ FIGYPIKLVV EKEREKEVED EEAVEAKDEE KKEGEVENVA 240
  241 DDADKKKTKK IKEKYFEDEE LNKTKPIWTR NPDDISNEEY AEFYKSLSND WEDHLAVKHF 300
  301 SVEGQLEFRA LLFVPQRAPF DLFENKKSKN SIKLYVRRVF IMENCEELMP EYLNFIKGVV 360
  361 DSEDLPLNIS REMLQQSKIL KVIRKNLVKK CMELIDEVAE DKDNFKKFYE QFGKNLKLGI 420
  421 HEDSTNRKKL SDFLRYSTSA GDEPTSLKEY VSRMKENQTQ IYYITGESKD VVAASAFVER 480
  481 VKSRGFEVLY MCDPIDEYCV QQLKEYDGKK LVSVTKEGLE LPETEEEKKK FEEDKVAYEN 540
  541 LCKVIKDILE KKVEKVGVSN RLVSSPCCIV TSEYGWSANM ERIMKAQALR DSSTMGYMAA 600
  601 KKHLEINPDH AIMKTLRDRV EVDKNDKTVK DLVVLLFETA LLASGFSLEE PQSHASRIYR 660
  661 MIKLGLDIGD DEIEDSAVPS SCTAEAKIEG AEEDASRMEE VD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered No Comments Cheeseman, I.M., et al. (2004)
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..702] PSI-BLAST 1000.0 No description for 2cg9A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle