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Protein Overview: CE04750

General Information:
Name(s) found: CE04750 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00019620 locus:fah-1 status:Confirmed UniProt:Q94272 protein_id:CCD72626.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 418 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: aromatic amino acid family metabolic process [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    metabolic process [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: catalytic activity [IEALink to PubMed article]
    fumarylacetoacetase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSFVSVPQN SDFPIQNLPY GVFSTKADSS RHIGVAIGDQ ILNLAEIANL FDGPQLKAHQ  60
   61 DVFKQSTLNA FMALPRPAWL EARARIQQLL SEDCAVLRDN AHLRSRALVA QSDATMHLPA 120
  121 QIGDYTDFYS SIHHATNVGI MFRGKENALM PNWKWLPVGY HGRASSIVVS GTDLKRPVGQ 180
  181 TKAPDAEVPS FGPSKLMDFE LEMAFFVGGP ENELGTRVPI EKAEDRIFGV VLMNDWSARD 240
  241 IQAWEYVPLG PFLAKSFATT VSPWVVSIEA LRPYFVENPV QDPVPPAYLH HDDPFTLDIN 300
  301 LAVSIRPEGD AVDHIVCKTN FKHLYWTLKQ QLAHHTVNGC NLRAGDLLGS GTVSGPEEGA 360
  361 YGSMLELSWR GAKEVPVGSE IRKFLKDGDE VNLSGVCEKN GVRIGFGECR GKVLPADI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..418] PSI-BLAST 131.0 Fumarylacetoacetate hydrolase, FAH, N-terminal domain; Fumarylacetoacetate hydrolase, FAH, C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, acting on acid carbon-carbon bonds
    		•  3.91949440356496 bayes_pls_golite062009
  • hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
    		•  3.81877470867258 bayes_pls_golite062009
  • fumarylacetoacetase activity
    		•  3.73784156823927 bayes_pls_golite062009
  • catalytic activity
    		•  1.43840931606572 bayes_pls_golite062009
  • binding
    		•  0.945020682808578 bayes_pls_golite062009
  • protein binding
    		•  0.211409325631147 bayes_pls_golite062009
  • hydrolase activity
    		•  0.00641900361184404 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle