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Protein Overview: pdi-2

General Information:
Name(s) found: pdi-2 / CE03972 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00003963 locus:pdi-2 Protein disulfide-isomerase 2 status:Confirmed UniProt:Q17770 protein_id:CCD63277.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 493 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed article][IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    glycerol ether metabolic process [IEALink to PubMed article]
    cell redox homeostasis [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    positive regulation of locomotion [IMPLink to PubMed article]
    Molecular Function: protein-glutamine gamma-glutamyltransferase activity [IDALink to PubMed article]
    protein disulfide isomerase activity [IDALink to PubMed articleLink to PubMed article]
    protein disulfide oxidoreductase activity [IEALink to PubMed article]
    electron carrier activity [IEALink to PubMed article]
    isomerase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRLVGLFFL VLGASAAVIE EEENVIVLTK DNFDEVINGN EFILVEFYAP WCGHCKSLAP  60
   61 EYAKAATQLK EEGSDIKLGK LDATVHGEVS SKFEVRGYPT LKLFRNGKPQ EYNGGRDHDS 120
  121 IIAWLKKKTG PVAKPLADAD AVKELQESAD VVVIGYFKDT TSDDAKTFLE VAAGIDDVPF 180
  181 GISTEDAVKS EIELKGEGIV LFKKFDDGRV AFDEKLTQDG LKTWIQANRL ALVSEFTQET 240
  241 ASVIFGGEIK SHNLLFVSKE SSEFAKLEQE FKNAAKQFKG KVLFVYINTD VEENARIMEF 300
  301 FGLKKDELPA IRLISLEEDM TKFKPDFEEI TTENISKFTQ NYLDGSVKPH LMSEDIPEDW 360
  361 DKNPVKILVG KNFEQVARDN TKNVLVEFYA PWCGHCKQLA PTWDKLGEKF ADDESIVIAK 420
  421 MDSTLNEVED VKIQSFPTIK FFPAGSNKVV DYTGDRTIEG FTKFLETNGK EGAGASEEEK 480
  481 AEEEADEEGH TEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..493] PSI-BLAST 68.69897 Crystal Structure of Yeast Protein Disulfide Isomerase


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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