YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: unc-78

General Information:
Name(s) found: unc-78 / CE03924 [WormBase]
Description(s) found:
Found 28 descriptions.
SHOW ALL
  • WBGene00006810 locus:unc-78 Actin-interacting protein 1 status:Confirmed UniProt:Q11176 protein_id:CCD63029.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 611 amino acids

    Gene Ontology:
    Cellular Component: sarcoplasm [IDALink to PubMed article]
    actomyosin, actin part [IDALink to PubMed article]
    Biological Process: barbed-end actin filament capping [ISSLink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    regulation of locomotion [IGI][IMP]
    negative regulation of actin filament polymerization [IDALink to PubMed article]
    positive regulation of actin filament depolymerization [IDALink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    skeletal muscle thin filament assembly [IMP]
    positive regulation of growth rate [IMPLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    positive regulation of locomotion [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: actin binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEFSQTALF PSLPRTARGT AVVLGNTPAG DKIQYCNGTS VYTVPVGSLT DTEIYTEHSH  60
   61 QTTVAKTSPS GYYCASGDVH GNVRIWDTTQ TTHILKTTIP VFSGPVKDIS WDSESKRIAA 120
  121 VGEGRERFGH VFLFDTGTSN GNLTGQARAM NSVDFKPSRP FRIISGSDDN TVAIFEGPPF 180
  181 KFKSTFGEHT KFVHSVRYNP DGSLFASTGG DGTIVLYNGV DGTKTGVFED DSLKNVAHSG 240
  241 SVFGLTWSPD GTKIASASAD KTIKIWNVAT LKVEKTIPVG TRIEDQQLGI IWTKQALVSI 300
  301 SANGFINFVN PELGSIDQVR YGHNKAITAL SSSADGKTLF SADAEGHINS WDISTGISNR 360
  361 VFPDVHATMI TGIKTTSKGD LFTVSWDDHL KVVPAGGSGV DSSKAVANKL SSQPLGLAVS 420
  421 ADGDIAVAAC YKHIAIYSHG KLTEVPISYN SSCVALSNDK QFVAVGGQDS KVHVYKLSGA 480
  481 SVSEVKTIVH PAEITSVAFS NNGAFLVATD QSRKVIPYSV ANNFELAHTN SWTFHTAKVA 540
  541 CVSWSPDNVR LATGSLDNSV IVWNMNKPSD HPIIIKGAHA MSSVNSVIWL NETTIVSAGQ 600
  601 DSNIKFWNVP F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..611] PSI-BLAST 111.0 Actin interacting protein 1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • dynein heavy chain binding
    		•  6.59987903164261 bayes_pls_golite062009
  • actin binding
    		•  3.86142918698875 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.1056443224755 bayes_pls_golite062009
  • dynein binding
    		•  3.03337063006717 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • actin filament binding
    		•  2.0735069176589 bayes_pls_golite062009
  • tubulin binding
    		•  1.71990413056683 bayes_pls_golite062009
  • microtubule binding
    		•  1.58000769768764 bayes_pls_golite062009
  • myosin heavy chain kinase activity
    		•  1.24520283111044 bayes_pls_golite062009
  • protein binding
    		•  1.21879977456466 bayes_pls_golite062009
  • transporter activity
    		•  1.21549336905926 bayes_pls_golite062009
  • receptor activity
    		•  1.12819778129653 bayes_pls_golite062009
  • myosin binding
    		•  0.989691178611801 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • signal transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.734793983890004 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.579815310385678 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.570141050045461 bayes_pls_golite062009
  • receptor binding
    		•  0.316169754698691 bayes_pls_golite062009
    		• 0.13154833491231 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.118975415284669 bayes_pls_golite062009
  • DNA binding
    		•  0.0736878329528894 bayes_pls_golite062009
  • snoRNA binding
    		•  0.0667470512746007 bayes_pls_golite062009
  • myosin II binding
    		•  0.0145748031956598 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.69

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle