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Protein Overview: CE03424

General Information:
Name(s) found: CE03424 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00010120 locus:dot-1.4 status:Partially_confirmed UniProt:Q20856 protein_id:CAA90610.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 383 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: histone-lysine N-methyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLFQIQNHE ENNVDKIESK MLEDETDLLH ETLSTVFPNG KSIKFDSHKH HVPVILLNML  60
   61 KELFEPVLNQ LSIELIAANG KTTNTDNVLA ELAKFNEAVA LFRRDNPKKQ LLLPKHWDQS 120
  121 TCTQQVAQKI TEIAKDLSVP YPKKLNQHYK GFSSETYGET MLEQIGSIVD ELKLNSSDVF 180
  181 VDLGSGIGQL VCFVAAYSKV KKAVGIELSS VPAEYAVSQG MYFKNLMTFF DKQHGEIELI 240
  241 QGDFLHPQFH DLICKEATVI FINNYAFEDD LTRRIVFELL QNCADGTRIV SAKPLSLPRS 300
  301 VASRRHAMSD FGSMSNSRTL RATESNVSWT SNIVEFTLTT VDHLKLFKSF EMQKESKKSA 360
  361 NSKVKKVGKD FTKTSLKNKK ESK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..383] PSI-BLAST 56.045757 Catalytic, N-terminal domain of histone methyltransferase Dot1l

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.723277178398499 bayes_pls_golite062009
  • transferase activity
    		•  0.64512166557639 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.54403439349476 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.54389223881989 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle