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Protein Overview: let-268

General Information:
Name(s) found: let-268 / CE03397 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00002497 locus:let-268 Procollagen-lysine,2-oxoglutarate 5-dioxygenase status:Confirmed UniProt:Q20679 protein_id:CAA91321.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 730 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IEALink to PubMed article]
    Biological Process: protein metabolic process [IEALink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [IEALink to PubMed article]
    procollagen-lysine 5-dioxygenase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVLPFLLPL IPVLLATTIT DLPELVVVTV ATENTDGLKR LLESAKAFDI NIEVLGLGEK  60
   61 WNGGDTRIEQ GGGQKIRILS DWIEKYKDAS DTMIMFVDAY DVVFNADSTT ILRKFFEHYS 120
  121 EKRLLFGAEP FCWPDQSLAP EYPIVEFGKR FLNSGLFMGY GPEMHKILKL KSVEDKDDDQ 180
  181 LYYTMIYLDE KLRKELNMDL DSMSKIFQNL NGVIEDVELQ FKEDGTPEAY NAAYNTKPLI 240
  241 VHGNGPSKSH LNYLGNYLGN RWNSQLGCRT CGLEVKESEE VPLIALNLFI SKPIPFIEEV 300
  301 LQKIAEFDYP KEKIALYIYN NQPFSIKNIQ DFLQKHGKSY YTKRVINGVT EIGDREARNE 360
  361 AIEWNKARNV EFAFLMDGDA YFSEPKVIKD LIQYSKTYDV GIIAPMIGQP GKLFTNFWGA 420
  421 IAANGYYARS EDYMAIVKGN RVGYWNVPFI TSAVLFNKEK LEAMKDAYSY NKNLDPDMSM 480
  481 CKFARDNGHF LYIDNEKYYG FLIVSDEYAE TVTEGKWHPE MWQIFENREL WEARYIHPGY 540
  541 HKIMEPEHVV DQACPDVYDF PLMSERFCEE LIEEMEGFGR WSDGSNNDKR LAGGYENVPT 600
  601 RDIHMNQVGF ERQWLYFMDT YVRPVQEKTF IGYYHQPVES NMMFVVRYKP EEQPSLRPHH 660
  661 DASTFSIDIA LNKKGRDYEG GGVRYIRYNC TVPADEVGYA MMFPGRLTHL HEGLATTKGT 720
  721 RYIMVSFINP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..264] FFAS03 1.44 Crystal Structural Analysis of Active Site Mutant Q189E of LgtC
    2 View Details [265..650] PSI-BLAST 3.221849 Dissection of mannosylglycerate synthase: an archetypal mannosyltransferase
    3 View Details [651..730] FFAS03 3.36 No description for 2hbtA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transferase activity
    		•  2.3313878748424 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.04659522044829 bayes_pls_golite062009
  • catalytic activity
    		•  1.73979371332125 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.641710647713692 bayes_pls_golite062009
  • binding
    		•  0.61043334112269 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.330936285354176 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  0.126802120207723 bayes_pls_golite062009
    2
    Term Confidence Notes
  • transferase activity
    		•  2.62166586999833 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.26676546016132 bayes_pls_golite062009
  • catalytic activity
    		•  1.88676710996045 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.03393419806381 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.796949457473955 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  0.619458068514795 bayes_pls_golite062009
  • binding
    		•  0.519359404396158 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  0.3992897623364 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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