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Protein Overview: vrk-1

General Information:
Name(s) found: vrk-1 / CE02704 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00017895 locus:vrk-1 Serine\/threonine-protein kinase VRK1 status:Confirmed UniProt:Q19848 protein_id:CCD61237.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 610 amino acids

    Gene Ontology:
    Cellular Component: ribosome [IEALink to PubMed article]
    intracellular [IEALink to PubMed article]
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    protein amino acid phosphorylation [IEALink to PubMed article]
    pronuclear envelope synthesis [IMPLink to PubMed article]
    translation [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    structural constituent of ribosome [IEALink to PubMed article]
    protein kinase activity [IEALink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPKKAPAKK LHELAAEVRV GHKINDISKK TFIVGKQFAT GGFGRIHTCT EEGKSQQMVM  60
   61 KIEPSTNGPL LTEVVVFNRI LKKELIESYK KKKKISWIGL PYLIANGYFT YESEKMRYMI 120
  121 IPKYATSLEA VRETNGGTLA MKDSLTVASC ILDALEYLHE SDYAHADVKA ANILLEKQGV 180
  181 YSTAVLVDFG LAHRTTNNVD KPDKKRAHNG TCIFTSTDAH RGNNPSFRGD IEILAYNLMM 240
  241 WATGTLPWMA LESSPEKVFD AKQKFIAGLP GTLQNVLKNE SSAVVGCIAS MFDISMKTNY 300
  301 TDKVDMGKLK KLVTDAIQKT SSDGKKTPTR QKKLAEEDKN AVTPKRSTRR LAVKEESDNK 360
  361 DNDEVEVKPE KKATPRKRTT RKAVEVNNDS DDNEEQYENP KSKSSRTQTK SKRAKEEDVD 420
  421 DEEEIIIPKS SRSRSKVQLS GEGSDVTTPS SAASTSRSRS IRLGLTSSTA SSNKVAKKIE 480
  481 QKYKRLSMNK SSLVPVTISV ASDKSPTTST PSSSSGLRSK RKSSEDVGEG ITLKTQVLIT 540
  541 PAIKKAKTKS GISSATKASP TELRRVPGVR NFPKGRRSMI IKETSAKYKE RLASRQTKPT 600
  601 FDDSSCSSEV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..333] PSI-BLAST 31.522879 No description for 2v62A was found.
    2 View Details [334..527] FFAS03 0.997 No description for 2j63A was found.
    3 View Details [528..610] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle