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Protein Overview: dnc-2

General Information:
Name(s) found: dnc-2 / CE01823 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00001018 locus:dnc-2 Probable dynactin subunit 2 status:Confirmed UniProt:Q09248 protein_id:CCD65975.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 331 amino acids

    Gene Ontology:
    Cellular Component: dynactin complex [IEALink to PubMed article][ISSLink to PubMed article]
    Biological Process: establishment of mitotic spindle orientation [IMPLink to PubMed article]
    pronuclear migration [IMPLink to PubMed articleLink to PubMed article]
    centrosomal and pronuclear rotation [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    nuclear migration [IMPLink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    microtubule-based process [IEALink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSIGKEDIY ESDGAASQVQ KSEPENDNPT HPDIELISVD VDEALKKYKN RVLNLTSSDF  60
   61 SDSIAKKRRH AFGNNQYVLE VTGAGFSGTE TAAEKLNRIL YEVADLNEQI RADENLKTDL 120
  121 LNAEVLENLE KEVKTLQVAQ SNGKTARVEH DVELPNVRTD SKVATLENRL RRIEQVIGSS 180
  181 VIPSAPVLDT IEDLKLRCET LNHSYVSGLE QRLNMMLTKL EKIDETRANN DIDENLDKKV 240
  241 DEILELMQKW DVACSSLPSN VNKVKALNRL HEQVQHFAGG LSHLKTIREK LEKEVAQGRE 300
  301 AIIEYESQGK QEIGSVVEKL KLLEAKVADL K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered No Comments Cheeseman, I.M., et al. (2004)
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..331] PSI-BLAST 17.0 Heavy meromyosin subfragment


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle