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Protein Overview: tag-124

General Information:
Name(s) found: tag-124 / CE01538 [WormBase]
Description(s) found:
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  • WBGene00006473 locus:tag-124 Probable tRNA pseudouridine synthase tag-124 status:Confirmed UniProt:Q09524 protein_id:CAA87378.1 [WormBase]
  • pir||T20413 hypothetical protein E02H1.3 - Caenorhabditis elegans [NCBI NR]
  • gi|71985046|ref|NP_496062.3| Temporarily Assigned Gene name family member (tag-124) [Caenorhabditis elegans] [NCBI NR]
  • gi|3875428|emb|CAA87378.1| C. elegans protein E02H1.3, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|1353139|sp|Q09524.1|TG124_CAEEL RecName: Full=Probable tRNA pseudouridine synthase tag-124; AltName: Full=tRNA-uridine isomerase; AltName: Full=tRNA pseudouridylate synthase [NCBI NR]
  • (Q09524) Probable tRNA pseudouridine synthase E02H1.3 (EC 5.4.99.-) (tRNA-uridine isomerase) (tRNA pseudouridylate synthase) [Swiss-Prot]
  • Probable tRNA pseudouridine synthase tag-124 OS=Caenorhabditis elegans GN=tag-124 PE=3 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • Hypothetical protein E02H1.3 [Caenorhabditis elegans]gi|7498308|pir||T20413 hypothetical protein E02H1.3 - Caenorhabditis elegansgi|1353139|sp|Q09524|YQN3_CAEEL Probable pseudouridylate synthase E02H1.3 (Pseudouridine synthase) [nrdb_11152004_Chlamydomonas]
  • CE01538 WBGene00006473 locus:tag-124 Yeast DEG-1 protein homolog status:Partially_confirmed SW:Q09524 protein_id:CAA87378.1 [wormpep150.fasta]
  • 01538 WBGene00006473 locus:tag-124 Yeast DEG-1 protein homolog status:Partially_confirmed SW:Q09524 protein_id:CAA87378.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • Yeast DEG-1 protein homolog status:Partially_confirmed SW:Q09524 protein_id:CAA87378.1 [wormpep115.fasta.reversed]
  • CE01538 Yeast DEG-1 protein homolog status:Partially_confirmed protein_id:CAA87378.1 [wormpep80.hongbin]
  • CE01538 WBGene00006473 locus:tag-124 Yeast DEG-1 protein homolog status:Partially_confirmed UniProt:TG124_CAEEL protein_id:CAA87378.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE01538 WBGene00006473 locus:tag-124 Yeast DEG-1 protein homolog status:Partially_confirmed UniProt:TG124_CAEEL protein_id:CAA87378.1| [wormORF-contam.fasta]
  • Hypothetical protein E02H1.3 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Temporarily Assigned Gene name family member (tag-124) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Probable tRNA pseudouridine synthase tag-124 (tRNA-uridine isomerase) (tRNA pseudouridylate synthase) [nr-271106-contam.fasta]
  • CE01538 WBGene00006473 locus:tag-124 Yeast DEG-1 protein homolog status:Partially_confirmed UniProt:Q09524 protein_id:CAA87378.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE01538 WBGene00006473 locus:tag-124 Yeast DEG-1 protein homolog status:Confirmed UniProt:Q09524 protein_id:CAA87378.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE01538 WBGene00006473 locus:tag-124 status:Confirmed UniProt:Q09524 protein_id:CAA87378.1 Probable tRNA pseudouridine synthase tag-124 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 402 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: tRNA processing [IEALink to PubMed article]
    Molecular Function: pseudouridylate synthase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSKRVCPDA NNSVKSKKAK TLDFLAHPRR KIAIQFFYLG WEHDGLVQQP HTQNTVENHI  60
   61 MQALIKTHLI EDWTKCDFSR CGRTDKGVSA FKQTAAMVVR SLCPGDSGVF WSDSTQEHQK 120
  121 VDYKASGEEL PYVKMLNGVL PKTIRVFAWA PVAQTFNARF DCNRRTYKYS FAKADLNLEK 180
  181 MRQGAELLVG EHDFSNFCQI DMNEKRLLQS YVRKVYEVKV EQVSTHPEND MYSMVELTVS 240
  241 GSGFLWHMIR YIVTILQEIG RENEQPSLIS QLLDLKKYPS RPQYTLASDT PLCLFDCGYK 300
  301 SEDVEWKVHD YTLKSTVTGL QKTWATYQAR SRMMENMLGE LTGMAEFSSG DANKGLHEFV 360
  361 QDRPIPSNYI RFENRKMCES LESKKEKMAE KKKNGEESSD KL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..307] PSI-BLAST 71.522879 No description for 2nqpA was found.
    2 View Details [308..402] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • pseudouridine synthase activity
    		•  5.60483019625575 bayes_pls_golite062009
  • intramolecular transferase activity
    		•  4.62815459483632 bayes_pls_golite062009
  • isomerase activity
    		•  3.43067391737824 bayes_pls_golite062009
  • catalytic activity
    		•  2.39224964671205 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle