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Protein Overview: die-1

General Information:
Name(s) found: die-1 / CE01501 [WormBase]
Description(s) found:
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  • WBGene00000995 locus:die-1 status:Confirmed UniProt:Q09478 protein_id:CAA88432.1 [WormBase]
  • pir||T19382 hypothetical protein C18D1.1 - Caenorhabditis elegans [NCBI NR]
  • gi|3874400|emb|CAA88432.1| C. elegans protein C18D1.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17532737|ref|NP_496175.1| Dorsal Intercalation and Elongation defect family member (die-1) [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE01501 WBGene00000995 locus:die-1 Zinc finger, C2H2 type (3 domains) status:Confirmed TR:Q09478 protein_id:CAA88432.1 [wormpep150.fasta]
  • 01501 WBGene00000995 locus:die-1 Zinc finger, C2H2 type (3 domains) status:Confirmed TR:Q09478 protein_id:CAA88432.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • C2H2 type zinc finger containing protein, Dorsal Intercalation and Elongation defect DIE-1 (die-1) [Caenorhabditis elegans]gi|3874400|emb|CAA88432.1| Hypothetical protein C18D1.1 [Caenorhabditis elegans]gi|7496271|pir||T19382 hypothetical protein C18D1. [nrdb_11152004_Chlamydomonas]
  • locus:die-1 Zinc finger, C2H2 type (3 domains) status:Confirmed TR:Q09478 protein_id:CAA88432.1 [wormpep115.fasta.reversed]
  • CE01501 locus:die-1 Zinc finger, C2H2 type (3 domains) status:Partially_confirmed TR:Q09478 protein_id:CAA88432.1 [wormpep80.hongbin]
  • CE01501 WBGene00000995 locus:die-1 Zinc finger, C2H2 type (3 domains) status:Confirmed UniProt:Q09478_CAEEL protein_id:CAA88432.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE01501 WBGene00000995 locus:die-1 Zinc finger, C2H2 type (3 domains) status:Confirmed UniProt:Q09478_CAEEL protein_id:CAA88432.1| [wormORF-contam.fasta]
  • Hypothetical protein C18D1.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Dorsal Intercalation and Elongation defect family member (die-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE01501 WBGene00000995 locus:die-1 Zinc finger, C2H2 type (3 domains) status:Confirmed UniProt:Q09478 protein_id:CAA88432.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE01501 WBGene00000995 locus:die-1 status:Confirmed UniProt:Q09478 protein_id:CAA88432.1 [wormpep246-ecoli-contam.fasta]
  • Dorsal Intercalation and Elongation defect OS=Caenorhabditis elegans GN=die-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 645 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    intracellular [IEALink to PubMed article]
    Biological Process: negative regulation of vulval development [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    actin filament organization [NASLink to PubMed article]
    morphogenesis of embryonic epithelium [IMPLink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    DNA binding [ISSLink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    transcription regulator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANAVDMQQL LMSMDPSSAN QFNMMNKGGA CVMATSGGSA SPTSSSGAPS SSSIMAETDE  60
   61 KDMFMPSQLI QNGLANNQLM SMILQQQSNQ ADSNIADAGH NNSGAEKNII ELLMSGNADL 120
  121 MKFATQFAQQ AKSVDQEPEE QRESSPSPPP AVSLNSTLAS MVFPTTSTAT ECSAASTTSS 180
  181 VDSAPSTVIV NGHSNSQSNT DDDDVTQQPS AKKQRTGDET PLTPTSNNQL MQSLLAQMGL 240
  241 SNPLHQQNQK QMKDESMMFS GLFPQGLAGI PLMFQSPLHQ QFAGMQDFEP LSALSTPNKG 300
  301 SGVKRQYSSN NKNFCDICNK EVCNKYFLRT HMLKMHGIVI DENKTVIANI DTSIKEREGE 360
  361 LTFRCDTCRT MFKTRNQLRQ HRQDVHGVLP LSTPRNNPNK SSVPTTPNGA NNNSGPNSAS 420
  421 MSEEKCALCD KRVSPSMMML HMAQDHFGAA AANGDLNQMM AILGQRNQST EEKMSSNLLE 480
  481 CTDCSYKTRD PKNLDLHMER HIKMSEAKGR GDEDEDVALQ LTTEAALQMV VQNQNQYDGD 540
  541 STAAALNLTF KNDGTKKEIE EEKATGNHER NSHTSGSISP SGSIPEGFGK NIGEKAFPTQ 600
  601 SFLIKCNDDS GEFLTEFLAQ LPVRSVIDGP RQLVFNLHPA PPTTS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..200] deduced N/A No confident structure predictions are available.
    2 View Details [201..344] PSI-BLAST 16.045757 Transcription factor IIIA, TFIIIA
    3 View Details [345..520] PSI-BLAST 52.0 No description for 2i13A was found.
    4 View Details [521..645] PSI-BLAST 16.221849 Five-finger GLI1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.5693324142242 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.20084827450202 bayes_pls_golite062009
  • DNA binding
    		•  1.11228868978256 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.10067326005752 bayes_pls_golite062009
  • transcription factor activity
    		•  0.33874886911135 bayes_pls_golite062009
  • protein binding
    		•  0.186544761618633 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  1.5693324142242 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.20084827450202 bayes_pls_golite062009
  • DNA binding
    		•  1.11228868978256 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.10067326005752 bayes_pls_golite062009
  • transcription factor activity
    		•  0.33874886911135 bayes_pls_golite062009
  • protein binding
    		•  0.186544761618633 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle