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Protein Overview: toc-1

General Information:
Name(s) found: toc-1 / CE01439 [WormBase]
Description(s) found:
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  • WBGene00006590 locus:toc-1 status:Confirmed UniProt:Q45EL5 protein_id:CCD66660.1 [WormBase]
  • gi|86563521|ref|NP_001033386.1| similar to Transporter Of divalent Cations family member (toc-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|71533334|gb|AAZ32791.1| Similar to transporter of divalent cations protein 1, isoform b [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE01439 WBGene00006590 locus:toc-1 status:Partially_confirmed TR:Q45EL5 protein_id:AAZ32791.1 [wormpep150.fasta]
  • 01439 WBGene00006590 locus:toc-1 status:Partially_confirmed TR:Q45EL5 protein_id:AAZ32791.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE01439 WBGene00006590 locus:toc-1 status:Confirmed UniProt:Q45EL5_CAEEL protein_id:AAZ32791.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE01439 WBGene00006590 locus:toc-1 status:Confirmed UniProt:Q45EL5_CAEEL protein_id:AAZ32791.1| [wormORF-contam.fasta]
  • Similar to transporter of divalent cations protein 1, isoform b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • similar to Transporter Of divalent Cations family member (toc-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE01439 WBGene00006590 locus:toc-1 status:Confirmed TR:Q45EL5 protein_id:AAZ32791.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE01439 WBGene00006590 locus:toc-1 status:Confirmed UniProt:Q45EL5 protein_id:AAZ32791.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • CE01439 WBGene00006590 locus:toc-1 status:Confirmed UniProt:Q45EL5 protein_id:CCD66660.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Similar to Transporter Of divalent Cations OS=Caenorhabditis elegans GN=toc-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 446 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: cation transport [IEALink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    Molecular Function: cation transmembrane transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEAMDFLKKN LNRVDFHSMV SFSWVSRSLH HPQGKRGLIS TLICLACVGI LAYCVSTSHS  60
   61 IVLMSTLWIT IFSFCSQFAS LYSMSITEKP THKFSYGLAR VPVLAVFSTT VLAQLFSIFL 120
  121 SKESFEHLLS PDHHGSHDAS AAHEHEVEEI GGWPYFVGSA ASSVALLLSA YALKNQPFQH 180
  181 VLQSATASSL QEHAADLSHA VCWVIPGLSR LLLPRINSMV LLALTTTGLN LLCEHFKHDF 240
  241 AWADPVCCLL LSVAVFSTMY PLSTYTGMIL LQTTPPHLIN QIDRCISEAS HIDGVLELKS 300
  301 GRFWQLDFNS LVGTVDVRVR RDADEQNVLA HVTEKFSSVI TVLTVQVVKD AAWSAGEQVP 360
  361 YSNGHIHKSE GNHSHDNGHG HSHDHNDHGH SHGHDDHGHD SHGHSHDHNE HDHGHSHGGN 420
  421 NDNHGHSHSA GSDNHHGHSH DGVFYH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..357] PSI-BLAST 41.154902 No description for 2qfiA was found.
    2 View Details [358..446] MSA 12.069995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transporter activity
    		•  0.0225298510244101 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.00888573638791978 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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